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THE AIM OF THE STUDY Was to analyze the efficacy achieved with regimens available for chronic hepatitis C (CHC) in Poland between 2013 and 2016. MATERIAL AND METHODS Data were collected from 29 centers and included 6786 patients with available sustained virologic response (SVR) data between 1 January 2013 and 31 March 2016. RESULTS The sustained virologic response rate for genotypes (G) 1a,...

Let [n, k, d]q-codes be linear codes of length n, dimension k and minimum Hamming distance d over GF (q). In this paper, the existence of the next recordbreaking codes [35, 7, 23]9, [42, 7, 29]9, [49, 7, 34]9, [56, 7, 40]9, [63, 7, 46]9, [98, 7, 75]9, [105, 7, 81]9, [112, 7, 87]9, [119, 7, 93]9, [126, 7, 99]9, [133, 7, 105]9, [48, 8, 32]9, [56, 8, 39]9, [104, 8, 78]9, [112, 8, 85]9, [120, 8, 91...

Abstract Background HIV-1C has been shown to have a greater risk of virological failure and reduced susceptibility towards boosted protease inhibitors (bPIs), component second-line combination antiretroviral therapy (cART) in South Africa. This study entailed an evaluation HIV-1 drug resistance-associated mutations (RAMs) among minor viral populations through high-throughput sequencing genotypi...

*,+ ' /. # 0,12. 0 ( # 3%& ) 45 76 . ) 6 8' 9% : 45 <; "='>0@?A &BC &%&' "$DE # & + .: "$6 #F "$6 #F 4$ : # ' # G% . # @"5 . ' H. . %I F"$ J' %& # "5 @ & -.K & "56 # L M N 12 < <O N & + /. # % 9' I. & BC !9P2 "5 . N & @ %& "$ N 8 )@ 9 . 4=0 ?A Q'I. 6 R ) 4=' 8"$#:.J . S &BC '9' 7 D . 4$) .T'

The title compound, C(24)H(56)N(4)P(6) or ((i)Pr(2)N)(2)P-P(4)-P(N(i)Pr(2))(2), adopts a butterfly structure, with planar environments for the N atoms and pyramidal environments for the P atoms. The structure studied has a 15% twin component that is related by a twofold rotation about [100].

Irreversible binding of T-even bacteriophages to Escherichia coli is mediated by the short tail fibres, which serve as inextensible stays during DNA injection. Short tail fibres are exceptionally stable elongated trimers of gene product 12 (gp12), a 56 kDa protein. The N-terminal region of gp12 is important for phage attachment, the central region forms a long shaft, while a C-terminal globular...

The cohomology of the moduli space M(n, d) of stable holomorphic vector bundles of coprime rank n and degree d over a fixed compact Riemann surface Σ of genus g ≥ 2 has been intensely studied over many years. In the case when n = 2 we now have a very thorough understanding of its structure [3, 24, 49, 56]. For arbitrary n it is known that the cohomology has no torsion [1], and inductive and clo...