Purposes: To assess the relationship between serum level of 25-hydroxyvitamin D (25(OH)D) and refractive error in Korean adolescents. Methods: A total of 2,038 adolescent aged 13-18 years, who participated in the Korea National Health and Nutrition Examination Survey (KNHANES) from 2008 to 2011 underwent refractive examination using an autorefractor. Serum 25(OH)D concentration and other potent...

PURPOSE To investigate the changes of posterior corneal elevation after small incision lenticule extraction (SMILE) for moderate and high myopia. METHODS In this prospective study, fifty consecutive eyes of thirty patients (10 male, 20 female) who underwent SMILE for myopia and myopic astigmatism were included. Eyes were divided in two groups based on the preoperative spherical equivalent ref...

Myopia is of diverse aetiology. A small proportion of myopia is clearly familial, generally early in onset and of high level, with defined chromosomal localisations and in some cases, causal genetic mutations. However, in economically developed societies, most myopia appears during childhood, particularly during the school years. The chromosomal localisations characterised so far for high famil...

The present study aimed to assess the microscopic changes of the epithelium and Bowman's layer under confocal microscopy during the early stages of severe myopia following laser in situ keratomileusis (LASIK). The study comprised 54 patients (54 eyes) with severe myopia and 65 patients (65 eyes) with low and moderate myopia, who underwent LASIK surgery at Tianjin Medical University Eye Hospital...

Purpose To test the hypothesis that genes known to cause clinical syndromes featuring myopia also harbor polymorphisms contributing to nonsyndromic refractive errors. Methods Clinical phenotypes and syndromes that have refractive errors as a recognized feature were identified using the Online Mendelian Inheritance in Man (OMIM) database. One hundred fifty-four unique causative genes were iden...

Myopia is a common ocular disorder characterized by refractive error affecting 30% of general population. High myopia (>6D) is caused by excessive axial elongation that primarily involves the ora-equatorial area and the posterior pole. Pathological myopia often accompanied by glaucoma, cataracts, macular degeneration, and retinal detachment, gradually leading to vision loss. Recent population a...

Pathological myopia is a major cause of irreversible vision loss and is the fourth to ninth most frequent cause of blindness in the world. Choroidal neovascularization (CNV) secondary to pathological myopia is the leading cause of vision impairment in patients younger than 50 years. New scientific contributions have been made to the understanding of high myopia and associated CNV. New treatment...

Nurture’ and ‘nature’ interact to produce myopia. This study probed the relation of myopia with the type of diet i.e. vegetarian or non-vegetarian, in young adults in India. One hundred forty eight young adults were tested for myopia and the odds of the vegetarian and non-vegetarian participants being affected were calculated. These were subjected to test of statistical significance. We report ...

High myopia is a common ametropia associated with significant risk of multiple comorbidities. Decreased visual functions myopic patients may be caused by non-specific diseases such as cataracts, glaucoma and rhegmatogenous retinal detachment, which are very likely in myopia. Yet especially important the specific changes atrophic, traction neovascular manifestations pathological myopia, totality...

In this study, the wave-front aberrations of medium and high myopia with different CCT after SMILE were studied by finite element method. Then, various trend clinical significance was obtained. When same, diopters different. increased, variations However, regardless degree myopia, defocus primary spherical aberration most obvious. The larger CCT, smaller absolute values aberration.