PURPOSE To test the hypothesis that posterior approach ptosis surgery, with or without blepharoplasty, can improve the cosmetic appearance of the eyelid. METHODS In a retrospective, observational, consecutive case cohort study, 261 patients who had posterior approach upper eyelid ptosis surgery with or without concurrent blepharoplasty performed by one surgeon, between 1997 and 2009, were rev...

BACKGROUND For patients with senile ptosis, aesthetic blepharoplasty can be combined with ptosis surgery. However, the amount of skin excision necessary in blepharoplasty is not clearly defined by measurements of the upper eyelids. OBJECTIVES The authors preoperatively evaluate the amount of skin to be excised in blepharoplasty. METHODS Fifty patients with bilateral senile ptosis were inclu...

To cite: Kumar S, Shukla R. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/ bcr-2014-207686 DESCRIPTION A 14-year-old boy presented with mild headache of 20 days duration and three episodes of vomiting over the past 3 days. On clinical evaluation, he had grade I papilloedema along with bilateral partial ptosis (figure 1). Extraocular movements, pupils and the rest of...

purpose: congenital third nerve palsy was generally thought to exist in isolation without associated abnormalities. in this report, we present a case of congenital third nerve palsy in osteogenesis imperfecta. methods: a 6-month-old girl with osteogenesis imperfceta presented with ptosis and large incomitant exotropia in left eye (le) at birth. ocular examination revealed total third nerve pals...

Myogenic differentiation is a highly orchestrated, multistep process that is coordinately regulated by growth factors and cell adhesion. We show here that integrin-linked kinase (ILK), an intracellular integrin- and PINCH-binding serine/threonine protein kinase, is an important regulator of myogenic differentiation. ILK is abundantly expressed in C2C12 myoblasts, both before and after induction...

The intrinsic ability of resistance arteries to respond to transmural pressure is the single most important determinant of their function. Despite an ever-growing catalogue of signalling pathways that underlie the myogenic response, it remains an enigmatic mechanism. The myogenic response's mechanistic diversity has largely been attributed to 'hard-wired' differences across species and vascular...

A case of giant hidrocystoma of the orbit in a 57-year-old female causing pain, epiphora and ptosis is reported. The cystic mass was totally excised as a whole. Histopathologic examination revealed eccrine hidrocystoma of the orbit. Hidrocystoma must be considered in the differential diagnosis of patients presenting with periocular masses causing pain and ptosis.

Myogenic cells migrate into the limb from the somitic mesoderm, taking up positions in the dorsal and ventral compartments before differentiating into the limb musculature. This process is influenced by the tissues of the limb in a number of ways. Cells of the lateral part of the somitic dermomyotome are induced to express a migratory myogenic phenotype by a diffusible signal originating in the...

BACKGROUND The health benefits of breast milk for infants are well documented, but breastfeeding is avoided by many women because of concerns about a negative effect upon breast appearance. However, there is very little objective data to either support or refute this view. OBJECTIVE The purpose of this study is to identify risk factors for the development of breast ptosis after pregnancy and ...