PURPOSE The aims of this study were to investigate the effects of manganese (Mn) dust exposure on lung functions and evaluate the potential synergistic effect between smoking and Mn dust exposure among refinery workers. METHODS A retrospective study including 1658 workers in a ferromanganese refinery was conducted, with subjects who were from the Guangxi manganese-exposed workers healthy coho...

Infectious molecular clones have been isolated from two maedi-visna virus (MVV) strains, one of which (KV1772kv72/67) is an antigenic escape mutant of the other (LV1-1KS1). To map the type-specific neutralization epitope, we constructed viruses containing chimeric envelope genes by using KV1772kv72/67 as a backbone and replacing various parts of the envelope gene with equivalent sequences from ...

Background: Diabetes mellitus is a leading public health problem with increasing incidence and long term complications such as diabetic nephropathy, diabetic neuropathy, diabetic retinopathy etc. These complications are mainly a consequence of macrovascular and microvascular damages of the target organs.The presence of an extensive microvascular circulation and abundant connective tissue in the...

BACKGROUND Small ruminant lentiviruses (SRLV) are members of the Retroviridae family and infect goats and sheep worldwide. Detection of specific antibodies using AGID and ELISA is the most commonly used means of diagnosing SRLV infection. The most frequent molecular method for detecting the provirus genome is PCR, using peripheral blood leucocytes as target cells. Real time PCR has also recentl...

To more systematically evaluate the effect of respiratory muscle rest on indices of ventilatory function, nine outpatients with stable, severe COPD were treated with nasal pressure-support ventilation delivered via a nasal ventilatory support system (BiPAP, Respironics, Inc) for 2 h a day for 5 consecutive days. An additional eight control patients were treated with sham-BiPAP. Maximum inspirat...

PURPOSE To evaluate the effect of posture and repetition of filling cystometry on urodynamic parameters. MATERIALS AND METHODS Seventy-one men with benign prostatic hyperplasia participated in a urodynamic study between September 2015 and August 2016 and were randomly assigned to a supine to supine (group SS, n=16), erect to erect (group EE, n=16), supine to erect (group SE, n=19) or erect to...

STUDY OBJECTIVE To determine whether the "hobble" or "hog-tie" restraint position results in clinically relevant respiratory dysfunction. METHODS This was an experimental, crossover, controlled trial at a university-based pulmonary function laboratory involving 15 healthy men ages 18 through 40 years. Subjects were excluded for a positive urine toxicology screen, body mass index (BMI) greater...

Zoonotic events of simian immunodeficiency virus (SIV) from non-human primates to humans have generated the acquired immunodeficiency syndrome (AIDS), one of the most devastating infectious disease of the last century with more than 30 million people dead and about 40.3 million people currently infected worldwide. Human immunodeficiency virus (HIV-1 and HIV-2), the two major viruses that cause ...

Large axial flow pump systems (LAPS) are widely used in coastal stations. In the actual operation of a LAPS, various accidents often occur during shutdown due to unreasonable control stop measures such as gate. this paper, based on secondary development Flowmaster numerical software, simulation study was conducted process LAPS with different gate laws. It found that MBV greater if closed more s...