Becker myotonia is a recessive muscle disease with prevalence of > 1:50,000. It is caused by markedly reduced function of the chloride channel encoded by CLCN1. We describe a Polish patient with severe myotonia, transient weakness, and muscle cramps who only responds to lidocaine. In addition, the patient has Prinzmetal angina pectoris and multiple lipomatosis. He is compound heterozygeous for ...

INTRODUCTION A recognised feature of Parkinson’s disease is the presence of muscle cramps. These are often attributed to dopaminomimetic medications and are known as early morning dystonia or ‘off’ dystonia. While these usually affect the truncal and upper limb musculature, patients can occasionally present with cramp-like calf pains which are frequently worse at night. The symptoms may be conf...

• General fatigue, exhaustion, apathy, lethargy and sleep disturbances • Central Nervous System headache, lightheadedness, fainting, forgetfulness, • Impaired memory, difficulty concentrating, confusion, irritability • Musculoskeletal pain in joints, neck and low back and muscle tenderness • Face and Pharynx sore throat, dry mouth, difficulty swallowing, atypical pain • Dermatologic – itching, ...

Background: Myopathies are a group of neuro muscular diseases that cause muscle weakness, cramps, and spasms due to primary defect the fiber. We undertook this study hereditary disorders identify clinical patterns laboratory findings in these conditions correlation between them, which will help recognizing them early for adequate management with rehabilitation measures prognostication. Aim: To ...

Internalised capillaries are described in the muscle fibres of two adult males who complained of exertional myalgia. In one patient, "bundles" of internalised capillaries were found in 2% of the Type 1 fibres and many of the Type 1 fibres exhibited non-specific cytoarchitectural changes. The other had hereditary motor and sensory neuropathy (HMSN) Type 2 and his muscle biopsy exhibited the more...