In 2012, mumps was introduced from Bosnia and Herzegovina to Vojvodina, causing an outbreak with 335 reported cases. The present manuscript analyses the epidemiological and laboratory characteristics of this outbreak, identifies its main causes and suggests potential future preventive measures. Sera of 133 patients were tested for mumps-specific antibodies by ELISA and 15 nose/throat swabs were...

BACKGROUND Infectious diseases after solid organ transplantation (SOT) are one of the major complications in transplantation medicine. Vaccination-based prevention is desirable, but data on the response to active vaccination after SOT are conflicting. METHODS In this systematic review, we identify the serologic response rate of SOT recipients to post-transplantation vaccination against tetanu...

OBJECTIVE To compare acute pain response to 2 measles-mumps-rubella vaccines. DESIGN Double-blind clinical trial. SETTING Hospital for Sick Children, Toronto, Ontario. Patients Forty-nine infants 12 months of age receiving their first measles-mumps-rubella vaccination. INTERVENTIONS Random allocation to receive Priorix or M-M-R II. MAIN OUTCOME MEASURES Pain responses before (baseline) ...

Background: Mumps is a self-limiting viral disease in children which usually resolve within 10 days. It characterized by fever, constitutional symptoms and swelling of the parotid gland(s) may lead to serious complications. The most common complication orchitis, followed meningitis. Less complications include pancreatitis, encephalitis, deafness, mastitis, oophoritis, facial Bell palsy. Methods...

Despite vaccination coverage over 95%, a measles outbreak started in May 2013 in the Netherlands. As of 28 August, there were 1,226 reported cases, including 82 hospitalisations. It is anticipated that the outbreak will continue. Most cases were orthodox Protestants (n=1,087/1,186; 91.7%) and unvaccinated (n=1,174/1,217; 96.5%). A unique outbreak control intervention was implemented: a personal...

Each year about 48,000 adults die from vaccine preventable diseases in the United States. The purpose of immunization programs is to prevent illness and death from diseases such as influenza, pneumococcal disease, hepatitis B, diphtheria, tetanus, measles, mumps, and rubella. The public health objectives established by Healthy People 2010 include a goal of achieving 90% immunization coverage of...

Adults born between 1966 and 1980 are at higher risk of measles, mumps and rubella, due to relatively low levels of immunity. Adults born before 1966 have probably been exposed to wild virus, and those born since 1980 have probably received two doses of measles, mumps, rubella (MMR) vaccine. Those born between 1966 and 1980 may not have had two doses because of changes in the immunisation sched...

OBJECTIVE To determine whether an evidence based decision aid on the measles, mumps, and rubella (MMR) vaccine changed parents' attitudes towards vaccination. DESIGN Before and after study. SETTING Website promoted through search engines and online parenting and health websites. PARTICIPANTS 158 people completing online questions out of 1277 who accessed the website. INTERVENTION Eviden...

Mathematical modelling is an established tool for planning and monitoring vaccination programmes. However, the matrices describing contact rates are based on subjective choices, which have a large impact on results. This paper reviews published models and obtains prior model probabilities based on publication frequency and expert opinion. Using serological survey data on rubella and mumps, Baye...

The aim of the study was to evaluate the usefulness of serological detection of mumps IgM and titration of IgG in patients with acute parotitis according to their vaccination status. The detection of mumps virus RNA in saliva by RT-PCR was used as reference. 116 patients (109 of them previously vaccinated) with mumps RT-PCR-negative results and 21 (19 vaccinated) with mumps RT-PCR-positive resu...