It is well known that unilateral profound sensorineural hearing loss is caused by mumps; however, bilateral deafness is rare. Herein we report a case of bilateral profound hearing loss caused by mumps infection in a four-year-old boy. Labyrinthitis due to the mumps virus was suspected. His verbal understanding was poor, and he completely stopped talking. He was soon fitted with a hearing aid, b...

The epidemiology of mumps in India and the magnitude of the problem are not fully appreciated(2). Outbreaks occur at interval of 5-10yrs(2). Mumps continue to occur in epidemic proportions despite the availability of an effective vaccine. Finland became the first documented country to be free of indigenous mumps and rubella with the use of national 2 dose trivalent MMR vaccination program, free...

INTRODUCTION: Neglected infectious diseases like mumps may be opportunistic in controlled areas with low vaccine coverage, particularly in developed and emerging countries. METHODS: A retrospective analysis of mumps-related data from 2001 to 2016 for São Paulo State, Brazil was conducted. RESULTS: From 2014 to 2015, there was an increase of 82% in reported mumps cases in São Paulo, with pre...

We present here the complete genome sequences of three mumps virus (MuV) strains isolated from patients who tested positive for the mumps virus during a mumps outbreak in Springdale, AR (USA), in 2016. The virus genomes, sequenced with Oxford Nanopore technology, belong to genotype G and have an average length of 15,342 nucleotides (nt).

Abstract Mumps is nowadays re-emerging despite vaccination. The contribution of T cell immunity to protection against mumps has not been clearly defined. Previously, we described a set 41 peptides that were eluted from human leukocyte antigen (HLA) class I molecules virus (MuV)-infected cells. Here, confirmed immunogenicity five novel HLA-B*07:02- and HLA-A*01:01-restricted MuV epitopes this pe...

Mumps virus produced a carrier state in human conjunctiva cells that was maintained for more than 100 subcultures over a period of 3 years. Antiserum in the medium was not required. The virus had little apparent effect on the cells which grew at a rate similar to uninfected control cells. Mumps virus was regularly found in the culture medium at levels about 0.9 log higher than the cell-associat...

INTRODUCTION Mumps is a common infectious disease. Epidemics of mumps are reported globally every year and represent a threat to public health, especially in China and other developing countries. METHODOLOGY Clinical and laboratory findings of 960 mumps patients admitted to Beijing You'an Hospital, China, between January 2010 and December 2012 were collected and analyzed. Patients with isolat...

BACKGROUND The measles-mumps-rubella (MMR) vaccine is effective in eliciting a good antibody response. In addition to the amount of antibodies, the avidity of these antibodies might be important in protecting against disease. METHODS The amount of circulating antibodies for measles, mumps, and rubella was measured with enzyme immunoassays, and the avidity of these antibodies was determined by...