Ganglioneuroma and neuroblastoma are tumors of similar origin; the latter is a rapidly growing, undifferentiated malignant type which may mature and differentiate into the former, a well-differentiated and usually benign type. Though both are neuroectodermal tumors, ganglioneuromas are composed of medullated or non-medullated nerve fibers and distinct mature ganglion cells [ 151, and in man, ar...

This report describes a case of multicentric intrahepatic biliary cystadenoma observed in a 13-year-old, male, Irish setter dog. The dog had a history of chronic inappetence, weight loss, intermittent icterus, and diarrhoea. In the ultrasonographic examination of the abdominal organs, 5 spherical masses were found in various liver lobes. The largest mass was 12 cm in diameter and was located on...

Liposarcoma is a common malignant soft tissue tumor, accounting for 10% to 16% of all sarcomas. Multicentric myxoid liposarcoma is an uncommon condition. Differentiation between several primary tumors and metastasis of a single liposarcoma represents the main difficulty in diagnosis. A 47-years old woman presented with right thigh myxoid liposarcoma and underwent wide margin tumor resection. Ot...

Multicentric reticulohistiocytosis (MRH) is an uncommon systemic disease of unknown aetiology, which is characterized by the presence of papulonodular lesions, and is caused by the proliferation of histiocytes associated with arthritis. There are only just 200 cases described in the scientific literature. It can behave like a paraneoplasia and may be malignant in a quarter of the patients. We w...

7. Mazzi R, Parisi SG, Sarmati L, et al. Efficacity of cidofovir on human herpesvirus 8 viraemia and Kaposi’s sarcoma progression in two patients with AIDS. AIDS. 2001;15:2061-2062. 8. Martin DF, Kuppermann BD, Wolitz RA, et al. Oral ganciclovir for patients with cytomegalovirus retinis treated with a ganciclovir implant. N Engl J Med. 1999; 340:1063-1070. 9. Parravicini C, Chandran B, Corbelli...

Synchronously occurring primary gynecological malignancies are rare, and most commonly reported synchronous female genital malignancies are ovarian and endometrial. It is postulated that the extended Mullerian system, comprising the ovarian epithelium, fallopian tube, uterine corpus and cervix, may respond as a single morphological unit to a carcinogenic process, thus producing primary tumours ...

Multicentric gliomas are uncommon lesions of the central nervous system. Their management remains controversial, but histopathologic diagnosis after complete or partial resection must be performed to differentiate these tumors from other multiple cerebral lesions. Three cases of multicentric glioma are presented, one of which had supra- and infratentorial lesions. Histological specimens were ob...

Despite the advancement made in the fields of neurosurgery, neuro-oncology, medical oncology, and radiation oncology, patients with recurrent high grade gliomas represent a unique challenge to the treating physicians [1,2]. Gliomas have the ability to disseminate along established CNS routes, such as white matter tracts, cerebrospinal fluid, or local invasion [3]. Multifocal appearance accordin...

Dermoid cysts are benign and congenital ectodermal inclusions. Their occurrence in an intracranial location is quite rare. They constitute 0.1 to 0.7% of all intracranial tumors. Their occurrence in the fourth ventricle and their multicentric feature are extraordinary. A 12-year-old boy was admitted to our clinic with a dermoid cyst with sixth cranial nerve involvement. He had symptoms of incre...