tin in 84 patients with multiple myeloma (MM) and in 13 healthy controls. The level of measured antiangiogenic agent was correlated with the phase and stage of the disease, and most importantly with clinical and laboratory parameters depicting the disease activity (haemoglobin, creatinine, albumins, calcium, M-component, C-reactive protein, b2-microglobulin, lactate dehydrogenase, stage of bone...

Imaging was performed using a 3T Siemens AG (Erlangen, Germany) Allegra MRI scanner at the UCLA Ahmanson-Lovelace Brain Mapping Center. For all subjects, whole-brain functional imaging was performed using a T2*-weighted echoplanar imaging (EPI) sequence with common parameters [repetition time (TR), 2 s; echo time (TE), 30 ms; flip angle, 90; matrix, 64 x 64; field of view (FOV), 200 mm; slice t...

Graph theory is also widely used as a representational form and characterization of brain connectivity network, as is machine learning for classifying groups depending on the features extracted from images. Many of these studies use different techniques, such as preprocessing, correlations, features or algorithms. This paper proposes an automatic tool to perform a standard process using images ...

Introduction: Temporal lobe epilepsy (TLE) presented with behavioral and psychiatric disorders is one of the most hectic forms of epileptic seizures, in which a uniform pathology cannot explain its manifestations, and structural underlying causes should be kept in mind. Case Presentation: This report described a 38-year-old female admitted to our department in emergency manner with episodic att...

Background Measures taken over the past four years in Greece to reduce pharmaceutical expenditure have led to significant price reductions for medicines, but have also changed patient cost-sharing rates for prescription drugs. This study attempts to capture the resulting increase in patients’ out-of-pocket (OOP) expenses for prescription drugs during the 2011-2014 period.   Methods The authors ...

This commentary discusses pertinent issues from Hyosun Kim’s paper on online prescription drug promotion. The study is well-designed and the findings highlight some of the consequences of the Food and Drug Administration’s (FDA’s) decision to deregulate online advertising of prescription drugs. While Kim’s findings confirm some of the early concerns, they also provide a perspective of implement...

Introduction Consistent scan plane prescription for Magnetic Resonance Imaging (MRI) is very important clinically for easy comparison of images across subjects and in serial evaluation of longitudinal exams. Typical workflow of scan plane set up requires careful manual positioning, and suffers from inter-operator variability. To date, some automated systems for brain imaging slice plane plannin...

Traditionally, medical prescriptions by doctors have been typically handwritten or printed by computer on paper and hand-delivered to pharmacists. Paperbased medical prescription is, however, causing increasing concern as incidences of prescription errors have been increasing causing minor to serious problems to patients, including deaths. Most of the errors of paper-based prescription could be...