22q11.2 Deletion Syndrome (22q11DS) is a common microdeletion disorder associated with mild to moderate intellectual disability and specific neurocognitive deficits, particularly in visual-motor and attentional abilities. Currently there is evidence that the visual-motor profile of 22q11DS is not entirely mediated by intellectual disability and that these individuals have specific deficits in v...

BACKGROUND AND PURPOSE The extensive application of advanced MR imaging techniques has undoubtedly improved our knowledge of the pathophysiology of amyotrophic lateral sclerosis. Nevertheless, the precise extent of neurodegeneration throughout the central nervous system is not fully understood. In the present study, we assessed the spatial distribution of cortical damage in amyotrophic lateral ...

Amyotrophic Lateral Sclerosis (ALS) is one of the most severe neurodegenerative diseases, which is known to affect upper and lower motor neurons. In contrast to the classical tenet that ALS represents the outcome of extensive and progressive impairment of a fixed set of motor connections, recent neuroimaging findings suggest that the disease spreads along vast non-motor connections. Here, we hy...

The goal of this paper is to examine the state current research and interests researchers all over world regarding relationship between physical activity psychophysical wellbeing (mental health) children with various types disability in context family. A systematic literature was conducted using Cochrane Library, EBSCO, PsycInfo PubMed databases. Available articles published 2010–2020 were sear...

Background: Children with attention deficit hyperactivity disorder/developmental coordination disorder (ADHD/DCD) suffer from problems associated with gross and fine motor skills. There is no effective pharmacological therapy for such patients. We aimed to assess the impact of methylphenidate (MPH) on motor performance of children with ADHD/DCD.Methods: In this double-blind placebo-controlled, ...

The fine motor skills of children with intellectual disabilities vary and are influenced by several factors including parents’ contributions. This study was set to determine the children's role parents in disabilities. subjects this were 47 aged 7-8 years their parents. Fine obtained through assessment using instruments Meanwhile, data on gathered a questionnaire. results showed that group most...