Analyzing usability improvement processes as they take place in real-life organizations is necessary to understand the practice of usability work. This paper describes a case study where the usability of an information system is improved and a relationship between the improvements and the evaluation efforts is established. Results show that evaluation techniques complemented each other by sugge...

The aim of this study was to investigate the convergent and divergent validity between the Body Coordination Test for Children (KTK) and the Motor Proficiency Test for 4- to 6-Year-Old Children (MOT 4-6). A total of 638 children (5-6 yr old) took part in the study. The results showed a moderately positive association between the total scores of both tests (rs = .63). Moreover, the KTK total sco...

PURPOSE The ability of visually impaired people to deploy attention effectively to maximize use of their residual vision in dynamic situations is fundamental to safe mobility. We conducted a pilot study to evaluate whether tests of dynamic attention (multiple object tracking; MOT) and static attention (Useful Field of View; UFOV) were predictive of the ability of people with central field loss ...

The subcellular localization, expression level, and activity of anti-cancer proteins alter in response to intrinsic and extrinsic cellular stresses to reverse tumor progression. The purpose of this study is to determine whether UBXN2A, an activator of the p53 tumor suppressor protein, has different subcellular compartmentalization in response to the stress of DNA damage. We measured trafficking...

The purpose of this study was to estimate the heritability of scrotal circumference (SC) and semen traits, genetic correlations between SC and semen quality traits, and the effect of cytoplasmic line on SC and semen traits. Breeding soundness exam (BSE) data were collected on registered Angus bulls at 4 ranches over 7 yr. The American Angus Association provided historical pedigree information t...

BACKGROUND Frequent handwashing can prevent infections, but non-compliance to hand hygiene is pervasive. Few theory- and evidence-based interventions to improve regular handwashing are available. Therefore, two intervention modules, a motivational and a self-regulatory one, were designed and evaluated. METHODS In a longitudinal study, 205 young adults, aged 18 to 26 years, were randomized int...

Veratridine (VTD), an alkaloid derived from the Liliaceae plant shows anti-tumor effects; however, its molecular targets have not been thoroughly studied. Using a high-throughput drug screen, we found that VTD enhances transactivation of UBXN2A, resulting in upregulation of UBXN2A in the cytoplasm, where UBXN2A binds and inhibits the oncoprotein mortalin-2 (mot-2). VTD-treated cancer cells unde...

Analyzing usability improvement processes as they take place in real-life organizations is necessary to understand the practice of usability work. This paper describes a case study where the usability of an information system is improved and a relationship between the improvements and the evaluation efforts is established. Results show that evaluation techniques complemented each other by sugge...

The multiple-object tracking paradigm (MOT) has been used extensively for studying dynamic visual attention, but the basic mechanisms which subserve this capability are as yet unknown. Among the unresolved issues surrounding MOT are the relative importance of motion (as opposed to positional) information and the role of various memory mechanisms. We sought to quantify the capacity and dynamics ...

30 Background: Frequent handwashing can prevent infections, but non-compliance to hand 31 hygiene is pervasive. Few theoryand evidence-based interventions to improve regular 32 handwashing are available. Therefore, two intervention modules, a motivational and a self33 regulatory one, were designed and evaluated. 34 Methods: In a longitudinal study, 205 young adults, aged 18 to 26 years, were ra...