More Hype Than HOPE To the Editor: In the recently published Heart Outcomes Prevention Evaluation (HOPE study),1 treatment with the ACE inhibitor ramipril was reported to reduce cardiovascular morbidity and mortality independent of blood pressure (BP) reduction. High-risk “normotensive” (BP 140/80 mm Hg) patients (n 9541) were randomized to receive either 10 mg of ramipril or placebo in additio...

The Nerve Growth Factor (NGF) is the prototypic member of the neurotrophin (NT) family, which plays an essential role in the development and functioning of the vertebrate nervous system. Although originally defined by their actions on neuronal survival and differentiation in the peripheral (PNS) and central nervous systems (CNS), accumulating data indicate the presence of extensive interactions...

As educated women, we were bewildered by our medical care, or lack thereof. Following prenatal diagnostics of trisomy 13 or 18, we chose to continue our pregnancies. We understood that our babies would most likely die in utero or soon after birth. To enable ourselves to make informed choices, we sought information from the internet. Here, it was discovered that some babies with these trisomies ...

The likelihood ratio method [BG96] provides a tool for the calculation of hedge ratios and risk parameters with Monte Carlo calculations. In this article, we present the extension of existing likelihood ratio methods to multiple underlyings and to higher order sensitivities such as the crossderivatives on the underlyings, and how the method can be used in a displaced diffusion [Rub83] framework...

New payment models and other trends are forcing hospitals to become far more than providers of inpatient care. Here are how four organizations are embracing this new reality.

©FFPRHC J Fam Plann Reprod Health Care 2007: 33(3) Introduction The terms ‘repeat abortion’ and ‘repeat aborter’ appear in the scientific literature from the early 1970s onwards. To begin with, the pejorative term ‘abortion recidivism’ was used by some.1 The initial concern appeared to be that women might be using abortion instead of contraception as a means of fertility control, with connotati...

1870. United Kingdom. Scenes from a divorce. Alfred Russel Wallace, the coinventor with Darwin of the theory of evolution through natural selection, completely captivated by the melodious song of the sirens hailing spiritualism landed definitively on the controversial shores of the treason. In effect, with his essay The Limits of Natural Selection as Applied to Man, Wallace turned his back on t...