3.2. Energy Minimization 1592 3.3. Adiabatic Mapping 1593 3.4. Molecular Dynamics 1593 3.4.1. Simulated Environment 1595 3.4.2. SHAKE 1595 3.4.3. Experimental Conditions 1596 3.4.4. Solvation 1596 3.5. Langevin Dynamics 1597 3.6. Brownian Dynamics 1597 3.7. Monte Carlo 1598 3.8. Simulated Annealing 1598 3.9. Nondynamic Methods 1598 3.9.1. Conformational Sampling 1598 3.9.2. Principal Component ...

Paul A. Bunn, University of Colorado John Minna, University of Texas Southwestern Medical Center Alexander Augustyn, University of Texas Southwestern Medical Center Adi Gazdar, University of Texas Southwestern Medical Center Youcef Ouadah, Stanford University Mark A. Krasnow, Stanford University Anton Berns, Netherlands Cancer Institute Elisabeth Brambilla, Grenoble University Natasha Rekhtman,...

By 2005, or sooner, the three billion code let1:ers of a repr«~sentative human genome will be known, along with thE! locations of all of its genes. Even today, however, the work is greatly acctelerating identification of disease..related genes. One outcome will be tlests for genetic components of risk in the majority of common illnesses. In the longer run, genetic discoveri«~s will surely lead ...