1,3-dipolar cycloaddition reaction of 1 mol or 2 mol of dibenzalaceton with 1 mol of non-stabilized azomethinylides generated in situ by decarboxylative condensation of isatin and proline or sarcosine give the novel new spiro-oxindolo(pyrrolizidines/ pyrrolidines) instead of bis-spirooxindolo( pyrrolizidines/ pyrrolidines).

The title compound, C(13)H(12)N(4)OS·0.5C(3)H(7)NO, contains four hydrazine mol-ecules and two solvent mol-ecules in the asymmetric unit. The dihedral angles between the pyridine and phenyl rings in the hydrazine mol-ecules are 67.51 (16), 68.28 (16), 81.36 (15) and 83.32 (15)°. In the crystal, the mol-ecules are linked by N-H⋯N, N-H⋯O and N-H⋯S hydrogen bonds.

In the asymmetric unit of the title salt, C(14)H(13)ClN(+)·C(7)H(7)O(4)S(-), there are two crystallographically independent mol-ecules for each component. Each cation adopts an E configuration with respect to the C=C bond and is slightly twisted; the dihedral angle between the pyridinium and benzene rings is 6.53 (7)° for one mol-ecule and 5.30 (7)° for the other. The meth-oxy groups in the ani...

There are two independent mol-ecules in the asymmetric unit of the title compound, C24H22N2O4S3. In each, the sulfonamide N atoms reveal nearly a trigonal-planar geometry with two S atoms of the O=S=O groups and one C atom of the thia-zole ring; the angles around the N atoms are between 117.00 (13) and 123.86 (9)°. The methyl-phenyl-sulfonyl groups are in anti conformations, forming dihedral an...

The title compound, [Sn(C(7)H(7))(2)Cl(2)], exists as a monomeric tetra-hedral mol-ecule. The Sn atom lies on a special position of site symmetry 2. Adjacent mol-ecules are linked into a linear chain running along the b axis of the monoclinic unit cell by Sn⋯Cl bridges of 3.7275 (4) Å.

Mol-ecules of the title compound, C(28)H(22)S(2), are located on a crystallographic mirror plane with one half-mol-ecule in the asymmetric unit. The dihedral angle between the phenyl ring and the naphthyl unit is 83.14 (7)°. In the crystal, mol-ecules are inter-connected by C-H⋯S and C-H⋯π inter-actions.

The title compound, C(7)H(5)Cl(2)NO(2), crystallizes with two independent mol-ecules in the asymmetric unit. The bond lengths and angles in both mol-ecules are within normal ranges. In the crystal structure, weak inter-molecular C-H⋯O hydrogen bonds link the mol-ecules into layers parallel to the [010] plane.

Human isolated digital arteries and metatarsal veins, obtained postmortem, have been used to compare the effects of alpha-adrenoceptor antagonists on contractile responses to nerve stimulation. The antagonists used were prazosin, rauwolscine, BE 2254, and yohimbine. Rauwolscine (alpha 2-antagonist), as well as prazosin and BE 2254 (alpha 1-antagonists), in concentrations of 10(-9), 10(-8), and ...

The asymmetric unit of the title compound, C(7)H(5)NS·0.5C(2)H(2)O(4), contains one benzothia-zole mol-ecule and half an oxalic acid mol-ecule, the complete mol-ecule being generated by inversion symmetry. The benzothia-zole mol-ecule is essentially planar, with a maximum deviation of 0.007 (1) Å. In the crystal, the benzothia-zole mol-ecules inter-act with the oxalic acid mol-ecules via O-H⋯N ...

The title compound, C(7)H(10)N(2)O, crystallizes with two independent mol-ecules in the asymmetric unit. The bond lengths and angles in the mol-ecules are within normal ranges. The crystal structure is stabilized by inter-molecular N-H⋯N hydrogen bonds, linking the two independent mol-ecules into hydrogen-bonded dimers.