Alumina toughened zirconia (ATZ) nanoceramics accompanied with high-strength, high-toughness and high-hardness were prepared by in-situ nanoprecipitation from using solid solution micro-powders. The submicron-sized Al2O3 (∼445 nm) ZrO2 (∼361 grains contained low-density precipitated nano-ZrO2 (∼35 nano-Y4Al2O9 (YAM, ∼87 particles, respectively, making high-performance nano-ATZ ceramics ultrafin...

In this study, Analytical Hierarchy Process (AHP) was employed to select the best method for the preparation of Nateglinide (NTG)loaded nanoparticles. There are various techniques available for the development of nanoparticles like Nanoprecipitation or Solvent displacement, Ionic gelation, Solvent evaporation method etc. and choosing the best method is a crucial one. AHP is one of the widely us...

We report here a unique method for formulating doxorubicin-polylactide (Doxo-PLA) conjugate nanoparticles, known as nanoconjugates (NCs), through Doxo/(BDI)ZnN(TMS)(2)-mediated [(BDI) = 2-((2,6-diisopropylphenyl)amido)-4-((2,6-diisopropylphenyl)-imino)-2-pentene], chemo- and regioselective polymerizations of lactide (LA) followed by nanoprecipitation. When Doxo/(BDI)ZnN(TMS)(2) was mixed with 1...

In this paper, the Kadomtsev-Petviashvili equation is solved by using the Adomian’s decomposition method , modified Adomian’s decomposition method , variational iteration method , modified variational iteration method, homotopy perturbation method, modified homotopy perturbation method and homotopy analysis method. The existence and uniqueness of the solution and convergence of the proposed...

Sustainable and safe delivery of brain-targeted drugs is highly important for successful therapy in Parkinson's disease (PD). This study was designed to formulate biodegradable poly(ethylene glycol)-poly(lactic-co-glycolic acid) (PEG-PLGA) nanoparticles (NPs), which were surface-modified with lactoferrin (Lf), for efficient intranasal delivery of rotigotine to the brain for the treatment of PD....

Over the last decade isoindigo derivatives have attracted much attention due to their high potential in pharmacy and in the chemistry of materials. In addition, isoindigo derivatives can be modified to form supramolecular structures with tunable morphologies for the use in drug delivery. Amphiphilic long-chain dialkylated isoindigos have the ability to form stable solid nanoparticles via a simp...

We report a facile and general strategy for enhancing the photostability of organic fluorophores for bioimaging applications. As a proof of concept, bright and robust fluorescence was observed in solid states of a well-defined synthetic polymer polycaprolactone consisting of di(thiophene-2-yl)-diketopyrrolopyrrole covalently linked in the middle of the polymer chain as a biocompatible and biore...

the presence of van der waals (vdw) force can lead to mechanical instability in freestanding nano-scale actuators. most of the previous researches in this area have exclusively focused on modeling the instability in actuators with one actuating components. while, less attention has been paid to actuators consist of two actuating components. herein, the effect of the vdw force on the instability...