In the coming years, the frequency of unauthorised genetically modified organisms (GMOs) being present in the European food and feed chain will increase significantly. Therefore, we have developed a strategy to identify unauthorised GMOs containing a pCAMBIA family vector, frequently present in transgenic plants. This integrated approach is performed in two successive steps on Bt rice grains. F...

The rapid increase in the number of genetically modified (GM) varieties has led to a demand for high-throughput methods to detect genetically modified organisms (GMOs). We describe a new dynamic array-based high throughput method to simultaneously detect 48 targets in 48 samples on a Fludigm system. The test targets included species-specific genes, common screening elements, most of the Chinese...

Two new 5-oxomilbemycins, 27-aldehyde-5-oxomilbemycin β12 (1) and 2-hydroxymilbemycin K (2), were isolated from a genetically engineered strain Streptomyces bingchenggensis BCJ60. Their structures were determined by comprehensive analyses of its 1 H and 13 C NMR, COSY, HMQC, and HMBC spectroscopic, HRESI-MS mass spectrometric and comparison with data from the literature. Preliminary studies sho...

Modern systems must be adaptable | to changing requirements, bugxes, new technologies and recon guration. For critical applications this must be possible at run-time; for complex applications it should be limitable to major sub-divisions of the system. The DRASTIC architecture addresses these goals by exploiting object persistence and distributed systems implementation techniques. It enables ru...

Rule finding is an important aspect of human reasoning and flexibility. Previous studies associated rule finding failure with past experience with the test stimuli and stable personality traits. We additionally show that rule finding performance is severely impaired by a mindset associated with applying an instructed rule. The mindset was established in Phase 1 (manipulation) of the experiment,...

Groundwater management and protection has been facilitated by computational modeling of aquifer vulnerability and monitoring aquifers using groundwater sampling. The DRASTIC (Depth to water, Recharge, Aquifer media, Soil media, Topography, Impact of vadose zone media, and hydraulic Conductivity) model, an overlay and index GIS model, has been used for groundwater quality assessment because it r...

The mechanisms wh(eeby, dietary sodium restriction leads to decreased arterial blood pressure is obscure. Previously reported studies of patients with arterial hypertension showed a lessened pressor response to norepinephrine after sodium restriction. In the present investigations, reduction in pressor response to norepinephrine during the low sodium period was observed only occasionally; sodiu...

Biosafety of genetically modified organisms (GMOs) and their derivatives is still a major topic in the agenda of government and societies worldwide. The aim of this review is to bring into light that data that supported the decision taken back in 1998 as an exercise to stimulate criticism from the scientific community for upcoming discussions and to avoid emotional and senseless arguments that ...