Metabolic syndrome (MetS) is a steering force for the cardiovascular diseases epidemic in Asia. This study aimed to compare the prevalence of MetS in Malaysian adults using NCEP-ATP III, IDF, and JIS definitions, identify the demographic factors associated with MetS, and determine the level of agreement between these definitions. The analytic sample consisted of 8,836 adults aged ≥30 years recr...

BACKGROUND Since the release of the 2013 American College of Cardiology/American Heart Association (ACC/AHA) guidelines, significant controversy has surrounded the applicability of the new cholesterol guidelines and the Pooled Cohort Equations. In this present study, we investigated whether eligibility for statin therapy determined by the 2013 ACC/AHA guidelines on the management of blood chole...

This study compared the prevalence of metabolic syndrome (MS) according to World Health Organization (WHO), National Cholesterol Education Program Third Adult Treatment Panel (NCEP-ATP III), International Diabetes Federation (IDF) and American Heart Association/ National Heart, Lung and Blood Institute (AHA/NHLBI) definitions, to evaluate how well the different classifications agreed. The study...

In a continuation of work on gene-enzyme relationships in histidine biosynthesis (1, 2) we have examined the early steps of the biosynthetic pathway in Salmonella typhimurium. It has been found that the first enzyme of the pathway catalyzes the condensation of 5-phosphoribosyl-1-pyrophosphate and adenosine triphosphate to form pyrophosphate and a product which has been isolated and characterize...

Purpose. Attapulgite was modified by sodium dihydrogen phosphate, oxalic acid-activated phosphate rock powder, potassium calcium superphosphate, ammonium and fused calcium-magnesium used in the remediation of Cd, Zn, Ni. Materials Methods. six kinds (ratio: 1 : 2), improvement effect passivation material on soil polluted cadmium, zinc, nickel determined. CaCl2-extractable toxicity characteristi...

OBJECTIVE To compare the prevalence of metabolic syndrome (MS) and the agreement of different diagnostic criteria for MS proposed by CDS (2004), IDF (2005) and NCEP-ATP III (2005). METHODS A crosssectional study of MS included 16,953 participants aged 35-74 was conducted in rural Henan Province in 2007 and 2008. The prevalence of MS was calculated by the three criteria and Kappa statistics wa...

BACKGROUND The aim of this study is to investigate the cardio-metabolic parameters and surrogate markers of insulin resistance in a discordant group of type 2 diabetes (T2DM) subjects who satisfy the Adults Treatment Panel (ATP) III criteria, but not the International Diabetes Federation (IDF) criteria, for metabolic syndrome (MetS). METHODS We assessed the prevalence of MetS in T2DM subjects...

The cellular ESCRT-III (endosomal sorting complex required for transport-III) and Vps4 (vacuolar protein sorting 4) comprise a common machinery that mediates a variety of membrane remodelling events. Vps4 is essential for the machinery function by using the energy from ATP hydrolysis to disassemble the ESCRT-III polymer into individual proteins. Here, we report the structures of the ATP-bound V...

OBJECTIVE Insulin resistance (IR) is an important risk factor for type 2 Diabetes Mellitus (DM2) and cardiovascular disease (CVD). Metabolic Syndrome (MS) is a clustering of metabolic alterations associated to IR; however, there is no international consensus for defining its diagnosis. Our objective was to evaluate the prevalence and characteristics of MS identified by the ATP III and IDF crite...

The updated clinical guidelines for cholesterol testing and management (Adult Treatment Panel (ATP) IV) from the Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults are under development and due to be published in 2012. These influential guidelines are organized and funded by the National Heart, Lung, and Blood Institute (NHLBI) and carry the imprimatur of t...