it was known that il-1β-induced rapid expression of mir-146a, which regulated the secretion of inflammatory chemokines in human a549 alveolar epithelial cells. however, little is known about the level of primary mir-146a and the downstream biogenesis of mir-146a in a549 cells. we examined the levels of primary mir-146a and mature mir-146a in a549 cells following treatment with pharmacological i...

Herein we discuss the impact of microRNA (miRNA) target genetic variability in male infertility genes, which can represent a source of novel molecular-genetic markers that can be used for the diagnosis of male infertility. Male-factor infertility accounts for 30%–40% of infertility cases. The causes of spermatogenetic failure found in most cases of non-obstructive azoospermia or severe oligozoo...

Circulating microRNAs have been recognized as promising biomarkers for the detection of lung cancer. The objective of this study was to evaluate miR-10b, miR-1 and, miR-30a in the plasma samples of lung cancer patients to confirm any possible relevance in the early detection of lung cancer. Plasma samples from 47 non-small-cell lung cancer patients and 41 cancer-free subjects were evaluated for...

The daily environmental exposure of humans to plasticizers may adversely affect human health, representing a global issue. altered expression microRNAs (miRNAs) plays an important pathogenic role in plasticizers. This systematic review summarizes recent findings showing the modified miRNAs cancer due Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodolo...

with a range of problem outcomes during childhood, adolescence and adulthood. Adults who were victims of child sexual abuse often fear sex, distrust their sex partners, have decreased sexual drive and have multiple superficial sexual relationships.1 Some children who were sexually abused have been found to engage in sexualized behavior (e.g., atypical sexual play with dolls and playmates, or ex...

Our previous study has suggested that downregulated microRNA (miR)-29a in denatured dermis might be involved in burn wound healing. However, the exact role of miR-29a in healing of burn injury still remains unclear. Here, we found that expression of miR-29a was notably upregulated in denatured dermis tissues and skin fibroblast cells after thermal injury, and thereafter gradually downregulated ...

Purpose – The purpose of this paper is to investigate why do people spectate eSports on the internet. The authors define eSports (electronic sports) as “a form of sports where the primary aspects of the sport are facilitated by electronic systems; the input of players and teams as well as the output of the eSports system are mediated by human-computer interfaces.” In more practical terms, eSpor...

The single underlying method of “averaging the wavelet functional over translates” yields first a new completeness criterion for orthonormal wavelet systems, and then a unified treatment of known results on characterization of wavelets on the Fourier transform side, on preservation of frame bounds by oversampling, and on the equivalence of affine and quasiaffine frames. The method applies to mu...