OBJECTIVE To determine clinical and follow up characteristics of children enrolled in a program to supply formulas for cow's milk allergy. METHODS descriptive study of a convenience sample composed of 214 children up to three years old, with clinical diagnosis of cow's milk allergy and/or standardized oral challenge, referred to the Program of Formulas for Cow's Milk Allergy at a Pediatric Un...

Background Cow’s milk proteins allergy (CMPA) is the most common food allergy in childhood, affecting up to 2.5% of infants. The immune mechanisms underlying non-IgE-mediated clinical presentations, which mostly affect the gastrointestinal system and are sometimes very severe, are not fully understood. Currently, specific oral tolerance induction (SOTI) is available as a specific treatment for ...

Cow milk allergy is a common disease of infancy, often associated with atopic dermatitis (AD). Avoidance of cow milk (CM) implies the use of alternative dietary supports such as mammalian milks. In this study, we assessed the tolerability and clinical effect of ass's milk (AM), when compared with the largely used goat's milk (GM) in a single-blind, controlled, randomized crossover. Twenty-eight...

Background Risk factors which promote the development of allergy to the cow milk protein in infants include antenatal sensitization, bottle feeding of neonates, early start of bottle or mixed feeding, postnatal sensitization of mite and pollen allergy. The aim of the study was to analyze a family history of the allergic diseases, course of pregnancy and delivery in mothers, effect of concomitan...

Although much is known today about the prevalence of food allergy in the developed world, there are serious knowledge gaps about the prevalence rates of food allergy in developing countries. Food allergy affects up to 6% of children and 4% of adults. Symptoms include urticaria, gastrointestinal distress, failure to thrive, anaphylaxis and even death. There are over 170 foods known to provoke al...

BACKGROUND Although the natural history of cow's milk allergy is to resolve during childhood or adolescence, a small but significant proportion of children will remain allergic. Specific oral tolerance induction to cow's milk (CM-SOTI) provides a treatment option in these children with continuing allergy with high success rates. However current sentiment limits widespread availability as existi...

The role of breastfeeding in improving allergy outcomes in early childhood is still unclear. Evidence suggests that immune mediators in human milk (HM) play a critical role in infant immune maturation as well as protection against atopy/allergy development. We investigated relationships between levels of immune mediators in colostrum and mature milk and infant outcomes in the first year of life...

Diverse therapeutic strategies for food allergy are under investigation including food allergen-specific and nonspecific approaches. Allergen-specific approaches include immunotherapy with native food allergens, immunotherapy with mutated recombinant allergens, and diets containing extensively heated milk or egg. Native allergen immunotherapy can be administered via oral, sublingual, subcutaneo...

We examined the characteristics of food allergy prevalence and suggested the basis of dietary guidelines for patients with food allergies and atopic dermatitis. A total of 2,417 patients were enrolled in this study. Each subject underwent a skin prick test as well as serum immunoglobulin E (IgE) measurement. A double-blind, placebo-controlled food challenge was conducted using milk, eggs, wheat...

can cause morbidity in the infant or mother (or both), through inadequate intake of dietary components, especially calcium.6 In extreme cases this can lead to rickets.6 Acutely, IgE mediated cow’s milk allergy can result in anaphylaxis, hypoxia, and shock. Chronically, either form can lead to anaemia, hypoalbuminaemia, and faltering growth. Accurate diagnosis and engagement of families is there...