Objective: The primary objective of this research is to assess the general population’s knowledge, attitude, and practice towards migraine. Method: A cross-sectional study was conducted on a total sample 255 participants. data were obtained from self-administered electronic questionnaire (Appendix) distributed through social media. Data analysis done using IBM Corp. Released 2019. SPSS Statisti...

Channelopathies are a heterogeneous group of neurological disorders resulting from dysfunction of ion channels located in cell membranes and organelles. The clinical scenario is broad and symptoms such as generalized epilepsy (with or without fever), migraine (with or without aura), episodic ataxia and periodic muscle paralysis are some of the best known consequences of gain- or loss-of-functio...

Introduction Migraine is a disease of the central nervous system characterized by moderate or severe headache. considered third most prevalent and seventh specific cause incapacity in world. The prevalence migraine women increase after menarche compared with men. According to previous population-based studies, during reproductive years, woman who has diagnosis menstrual experiences same symptom...

Background
 Migraine was previously interpreted as “benign” disease since the major part of patients were asymptomatic between attacks and brain lesions are absent in primary headaches. Advances structural neuroimaging have changed this point view. Voxel-based-morphometry is an accurate technique to evaluate objectively damage. Our hypothesis that some clinical features migraine, aura atta...

OBJECTIVES To examine the association between migraine and migraine aura status with risk of haemorrhagic stroke. DESIGN Prospective cohort study. SETTING Women's Health Study, United States. PARTICIPANTS 27,860 women aged >or=45 who were free from stroke or other major disease at baseline and had provided information on self reported migraine, aura status, and lipid values. MAIN OUTCOM...

background: migraine is a prevalent disease which is classified into two groups of migraine with aura and without aura. eighteen percent of women and 6.5 percent of men in united states have migraine headache. migraine headache is prevalent in all age groups but it usually subsides in adults above fifty. migraine has many risk factors such as stress, light, tiredness, special foods and beverage...

PURPOSE OF REVIEW Migraine is a prevalent neurovascular brain disorder with a strong genetic component, and different methodological approaches have been implemented to identify the genes involved. This review focuses on pearls and pitfalls of these approaches and genetic findings in migraine. SUMMARY Common forms of migraine (i.e. migraine with and without aura) are thought to have a polygen...

Migraine is a multifactorial disorder in which both multiple genetic (estimated at up to 61%) and nongenetic factors are contributing to the disease risk (for review see 1). Unravelling its molecular basis will undoubtedly help to elucidate the underlying mechanisms for the migraine trigger threshold and may ultimately lead to novel prophylactic treatment targets (2). Finding genes for the comm...

Migraine is classified by the World Health Organization (WHO) as being one of the top 20 most debilitating diseases. According to the neurovascular hypothesis, neuroinflammation may promote the activation and sensitisation of meningeal nociceptors, inducing the persistent throbbing headache characterized in migraine. The tumor necrosis factor (TNF) gene cluster, made up of TNFα, lymphotoxin α (...

BACKGROUND It was previously shown that the MTHFR gene polymorphism correlated with an increased risk of migraine, particularly migraine with aura. The substitution of cytosine for thymine at the position 677 of the MTHFR gene leads to formation of the thermolabile form of the protein and development of hyperhomocysteinemia, which increases the probability of migraine. The purpose of this study...