Single cell of vegetative microspore from spore-bearing plant field Equisetum arvense L. has been presented as a single-cell experimental model for the screening native compounds acting antihistamine agents. The effects azulene, sesquiterpene lactones austricine, gaillardine, grosshemine, inulicine, and desacetylinulicine well alcohol ledol, on content histamine in germinating horsetail microsp...