AIM To assess five main histological features of gastritis in gastric mucosa colonized with Helicobacter pylori before and after the treatment. METHODS Histologic assessment of H. pylori-associated gastritis was performed according to the Sydney classification before and after the treatment in 97 patients. Two additional parameters - the presence of lymphocytic aggregates and coccoid forms of...

The frequency and pattern of activity in the reciprocally connected GABAergic external globus pallidus (GPe) and glutamatergic subthalamic nucleus (STN) are closely related to motor function. Although phasic, unitary GPe-STN inputs powerfully pattern STN activity ex vivo, correlated GPe-STN activity is not normally observed in vivo. To test the hypothesis that the GPe's influence is constrained...

Science can be as stimulating to the eye as it is to the mind, according to Felice Frankel, 'artist in residence' at the Massachusetts Institute of Technology. She is working with researchers there to help them find better ways of communicating their work visually. Although she started out as a biologist, Frankel has also had a successful career as a landscape and architectural photographer. No...

First, I will recount the substance of several important conversations I had with Ilya Prigogine over the years. There is no doubt in my mind that Professor Prigogine firmly believed in the underlying stochasticity of the universe. Second, I will summarize my curiosity about the principle of detailed balance. In my opinion, so far it has always been put in by hand. Third, I will advance my own ...

Microscopic polyangiitis is a systemic vasculitis affecting smal-l and medium-sized vessels and is characteristically associated with a focal and segmental necrotizing glomerulonephritis. It may present as a pulmonary-renal syndrome with rapidly progressive glomerulonephritis and alveolar hemorrhage, but the pattern of disease will vary according to the organ systems involved. Granulomatous dis...

1 A subsequent household interview that compared six Vermont hospital service areas with widely varying spending and utilization rates showed no differences in self-reported illness, insurance coverage, ethnicIn 1967, fresh out of my medical training at Johns Hopins, I took a job as director of Vermont’s Regional Medical rogram (RMP) at the University of Vermont. The Vermont MP was part of a na...