The kinetic parameters of single bonds between neural cell adhesion molecules were determined from atomic force microscope measurements of the forced dissociation of the homophilic protein-protein bonds. The analytical approach described provides a systematic procedure for obtaining rupture kinetics for single protein bonds from bond breakage frequency distributions obtained from single-molecul...

Abstract The local field correction to the spontanous dacay rate of an impurity source atom imbedded in a disordered dielectric is calculated to second order in the dielectric density. The result is found to differ from predictions associated with both ”virtual” and ”real” cavity models of this decay process. However, if the contributions from two dielectric atoms at the same position are inclu...

Non-supersymmetric black holes carrying both electric and magnetic charge with respect to a single Kaluza-Klein gauge field have much in common with supersymmetric black holes. Angular momentum conservation and other general physics principles underlies some of their basic features. Kaluza-Klein black holes are interpreted in string theory as bound states of D6-branes and D0branes. The microsco...

The ab-initio analysis of a continuous system starts with the microscopic theory of the material, usually expressed in terms of partial differential equations, while a system analysis starts with its global properties and interconnections. These two ends must meet for an accurate and effective model of continuous systems. The macroscopic interaction between components is consistently defined by...

We consider the CFT that arises from the D1-D5 system in the presence of a constant background gauge potential which couples to the R-charge of the theory: this potential effectively changes the periodicities of the fermions. By the AdS/CFT correspondence, the effect of this connnection should be obtained by finding a smooth solution to the vector field in AdS space which couples to the constan...

We describe a numerical investigation of a continuum model of an active nematic, concentrating on the regime of active turbulence. Results are presented for the effect of three parameters, activity, elastic constant and rotational diffusion constant, on the order parameter and flow fields. Defects and distortions in the director field act as sources of vorticity, and thus vorticity is strongly ...

Purpose: The fundamental spatial resolution of in vivo MR lung imaging is limited by motion in thoracic cavity [1]. This problem is particularly evident in microscopic lung imaging of rodents because of their high cardiac (400-700 bpm) and breathing rate (100-150 breaths/min). To overcome these limitations several methods have been proposed, including scan-synchronous ventilation [2] and cardia...

We consider the motion of a contact line between a fluid, gas, and solid, as it occurs when a drop advances over a solid surface. This motion is controlled by a microscopic length scale near the contact line, such as a slip length or the precursor thickness. The capillary profile inside the drop is linked to the contact line through an intermediate region which is characterized by an interface ...

The dissolution dynamics of microscopic oil droplets (less than 1 μm in height, i.e. nanodroplets) on a hydrophobilized silicon surface in water was experimentally studied. The lateral diameter was monitored using confocal microscopy, whereas the contact angle was measured by (disruptive) droplet polymerisation of the droplet. In general, we observed the droplets to dissolve in a mixed mode, i....