In the field of positron emission tomography (PET) radiochemistry, compact microreactors provide reliable and reproducible synthesis methods that reduce the use of expensive precursors for radiolabeling and make effective use of the limited space in a hot cell. To develop more compact microreactors for radiosynthesis of 18F-labeled compounds required for the multistep procedure, we attempted ra...

Our recent studies of CO preferential oxidation (PrOx) identified systemic differences between the characteristic curves of CO conversion for a microchannel reactor with thin-film wall catalyst and conventional packed-bed lab reactors (m-PBR’s). Strong evidence has suggested that the reverse water-gas-shift (r-WGS) side reaction activated by temperature gradients in m-PBR’s is the source of the...

Colloidal perovskite nanocrystals comprised of all inorganic cesium lead halide (CsPbX3, X = Cl, Br, I or a mixture thereof) have potential as optical gain materials due to their high luminescence efficiency. In this work, cesium lead halide nanocrystals are continuously synthesized via a microreactor system consisting of poly(tetrafluoroethylene) (PTFE) capillaries. The synthesized nanocrystal...

In the present work, a continuous microreactor was designed to study the effect of miniaturization on bioreactors for the production of invertase from S. cerevisiae MM01 in a microfluidic environment. In order to simplify the analysis and considering typical production strategies at laboratory scale, 250 ml baffled flasks and a 2.5 l batch bioreactor were used as bench-scale models for the perf...

Isoquercitrin is a rare flavonol glycoside with a wide range of biological activities and is a key synthetic intermediate for the production of enzymatically modified isoquercitrin. In order to establish an ultrafast bioprocess for obtaining isoquercitrin, a novel continuous flow biosynthesis of isoquercitrin using the hesperidinase-catalyzed hydrolysis of rutin in a glass–polydimethylsiloxane ...

Microreactors have been widely used with advantageous of large specific surface area, excellent heat and mass transfer performance. In this paper, experimental numerical study were carried out to analyze the thermal hazard associated synthesis isopropyl propionate in a microreactor. study, effects reaction temperature, catalyst amount, channel diameter flow rate investigated. The optimal condit...