Fundamental research has made huge efforts in order to analyze big amounts of data stored in electronic databases, developing the so-called ”data mining” techniques. At the same time, in recent years, an enormous quantity of biological data has been produced, by means of some techniques recently developed in order to analyze cellular gene expression. The analysis of such data can not be perferm...

MOTIVATION An important task in microarray data analysis is the selection of genes that are differentially expressed between different tissue samples, such as healthy and diseased. However, microarray data contain an enormous number of dimensions (genes) and very few samples (arrays), a mismatch which poses fundamental statistical problems for the selection process that have defied easy resolut...

Background: Maternal mRNA degradation is a selective process that occurs in waves corresponding to important developmental transitions such as resumption of meiosis, fertilization and zygotic genome activation. It has been demonstrated that the number, position, and combination of 3 UTR cis-acting elements interacting with trans-acting protein factors regulate translation and mRNA stability. Ou...

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b a c k g r o u n d  & aim: it is very helpful to classify and predict the clinical  category  of a sample based  on  its  gene  expression  profile.  this  study  was  conducted  to predict  tissues  of colorectal adenoma,  adenocarcinoma,  and  paired  normal  in  colon  based  on  microarray  data  using  nearest shrunken centroid method. methods   &  materials:    in  this  study,   the  co...