With the development of nanotechnology, more nanomaterials will enter into water environment system. Studying the existing form of nanomaterials in water environment will help people benefit from the correct use of them and to reduce the harm to human caused by them for some nanomaterials can bring polluting effect. Aggregation is a main behavior for nanoparticle in water environment. NZVI are ...

Cell laden biomaterials are archetypically seeded with individual cells and steered into the desired behavior using exogenous stimuli to control growth and differentiation. In contrast, direct cell-cell contact is instructive and even essential for natural tissue formation. Namely, microaggregation and condensation of mesenchymal progenitor cells triggers chondrogenesis and thereby drives limb ...

N-cadherin cDNA was cloned from a zebrafish embryonic cDNA library. Analysis of the deduced amino acid sequence of this molecule (ZN-cadherin) revealed a high degree of homology to N-cadherins of other species, except that its pre-sequence is considerably shorter. Nevertheless, following transfection into Chinese hamster ovary (CHO) cells, the expressed protein was functionally active, namely p...

Although homo-oligomerization has been reported for several G protein-coupled receptors, this phenomenon was not studied at low concentrations of receptors. Furthermore, it is not clear whether homo-oligomerization corresponds to an intrinsic property of nascent receptors or if it is a consequence of receptor activation. Here CCR5 receptor oligomerization was studied by bioluminescence resonanc...

Immune thrombocytopenia (ITP) is an autoimmune disease with a complex heterogeneous pathogenesis and a bleeding phenotype that is not necessarily correlated to platelet count. In this study, the platelet function was assessed in a well-defined cohort of 33 pediatric chronic ITP patients. Because regular platelet function test cannot be performed in patients with low platelet counts, 2 new assay...

Mobile communication has grown quickly in the last two decades. Connections can be wirelessly established from almost any habitable place in the earth, leading to a plethora of connection-based tracking mechanisms, such as GPS, GSM, RFID, etc. Trajectories representing the movement of people are consequently being gathered and analysed in a daily basis. However, a trajectory may contain sensiti...

It is quite common that companies and organisations require of releasing and exchanging information related to individuals. Due to the usual sensitive nature of these data, appropriate measures should be applied to reduce the risk of re-identification of individuals while keeping as much data utility as possible. Many anonymisation mechanisms have been developed up to present, even though most ...

Parkinson's disease (PD), the most common neurodegenerative disorder, is characterized by abnormal accumulation of α-synuclein aggregates known as Lewy bodies (LB) and loss of nigrostriatal dopaminergic neurons. Recent neuroimaging studies suggest that in the early phases of PD, synaptic and axonal damage anticipate the onset of a frank neuronal death. Paralleling, even post mortem studies on t...

We address the problem of designing quantizers that cluster data while satisfying a k-anonymity requirement. A general data compression perspective is adopted, which considers both discrete and continuous probability distributions, and corresponding constraints on both cell sizes and quantizer index probabilities. Potential applications of this problem extend well beyond the important case of m...

The usual approach to generate k-anonymous data sets, based on generalization of the quasi-identifier attributes, does not provide any control on the variability of the confidential attributes within the k-anonymous groups. If the latter variability is too small, privacy is not sufficiently protected, while, for large variabilities, data utility is substantially damaged. Some refinements to the...