In this study, nanofibers with different ratios of poly(vinyl alcohol) and chitosan incorporated moxifloxacin hydrochloride (MH/PVA/CS) were fabricated through the blending electrospinning, morphological features tested using scanning electron microscopy (SEM). Further characterization new nanofiber was accomplished by Thermogravimetric analysis (TG), X-ray diffraction (XRD) Fourier-transform i...

Malignant hyperthermia (MH) has been reported as non-existent in children less than 1 yr old, although several unconfirmed reports have been published. A case report of MH in a 6-month-old child is presented, with confirmation of MH susceptibility by in vitro contracture testing of quadriceps muscle at 13 yr old. Genetic analysis revealed a novel RYR1 mutation that substitutes arginine 2452 for...

Schwartz-Jampel syndrome (SJS) is a rare syndrome that is clinically characterized by myotonia and skeletal abnormalities. Most reports regarding SJS have stated that patients with SJS are susceptible to malignant hyperthermia (MH). The statement is incorrect. There is no report showing that SJS is related to MH. Scientific evidence also shows that patients with myotonias are not susceptible to...

Background This study aims to investigate gene expression in skeletal muscle in relation to age and MH status, focussing on particular genes of interest. Expression patterns have been analysed to address the question of whether major causative malignant hyperthermia (MH) mutations influence skeletal muscle ageing. In this context we have examined gene expression in MH susceptible, both with (MH...

The ability to judge a nation’s scientific standing is vital for the governments, businesses and trusts that must decide scientific priorities and funding. In this paper I analyse the output and outcomes from research investment over the past decade, to measure the quality of research on national scales and to set it in an international context. There are many ways to evaluate the quality of sc...

Immigrants are less likely than others to use mental health (MH) services. Physicians' limited time often precludes inquiry about MH. This study investigated the influence of generational status, ethnicity, and mental/substance use disorders on physicians' inquiries about Asian American (AA) MH. Data from the National Latino and Asian American Study were analyzed (n=1,853). The outcome was past...

A new high peak power density alkaline fuel cell ~FC! was fabricated using a metal hydriding ~MH! alloy as the anode electrocatalyst and manganese dioxide as the cathode electrocatalyst. The high-loading MH and MnO2 electrocatalysts not only gave a satisfactory steady-state power output, but also deliver additional power stored in the charged MH and MnO2 electrodes when the overall cell voltage...

In this article, we show that magnitude homology and path are closely related, give some applications. We define differentials MH k ℓ ( G ) ⟶ − 1 $\operatorname{MH}^{\ell }_k(G) \longrightarrow \operatorname{MH}^{\ell -1}_{k-1}(G)$ between homologies of a digraph $G$ , which make them chain complexes. Then its $\mathcal {MH}^{\ell }_k(G)$ is non-trivial homotopy invariant in the context ‘homoto...

There is renewed interest in the potential use of natural compounds in cancer therapy. Previously, we demonstrated the anti-tumor properties of manuka honey (MH) against several cancers. However, the underlying mechanism and molecular targets of this activity remain unknown. For this study, the early targets of MH and its modulatory effects on proliferation, invasiveness, and angiogenic potenti...

From the LEP precision data, upon excluding the observables Rb, Rc in a combined fit of the top-quark mass, mt, and the Higgs-boson mass, MH, within the Standard Model, we find the weak 1σ bound of 40GeV < ∼ MH < ∼ 1TeV. Stronger upper bounds on MH, sometimes presented in the literature, rely heavily on the inclusion of Rb in the data sample. Upon including Rb, the quality of the fit drasticall...