MANAGEMENT of neuropathic pain is not an easy task, especially after pain is well established. Practitioners choose from a bewildering array of ingredients to create their own menus, based on local taste and local experience, with little literature serving up a gold-standard, prize-winning combination. “Morphine versus Mexiletine for Treatment of Postamputation Pain: A Randomized, Placebo-contr...

Primary erythromelalgia (PE) is an autosomal dominant neurological disorder characterized by severe burning pain and erythema in the extremities upon heat stimuli or exercise. Mutations in human SCN9A gene, encoding the α-subunit of the voltage-gated sodium channel, Na(v)1.7, were found to be responsible for PE. Three missense mutations of SCN9A gene have recently been identified in Taiwanese p...

BACKGROUND Postherpetic neuralgia is pain that persists long after the disappearance of the cutaneous lesions of herpes zoster. However, the mechanisms of this delayed pain are unclear. Herpes simplex virus infection induces cutaneous lesions and pain-related responses in mice. The authors examined whether such responses would persist after the disappearance of the cutaneous lesions and whether...

Cardiac stereotactic body radiotherapy (SBRT) is a novel therapy for refractory ventricular tachycardia (VT). However, there remain knowledge gaps due to limited experience. The wireless stimulation endocardial cardiac resynchronization (WiSE CRT) promising method of left (LV) using receiver electrode implanted in LV and transmitter the intercostal space that connected subcutaneous battery. saf...