An acute acoustic trauma (AAT) results when the unprotected ear is exposed to very high sound pressure levels, usually as the result of an industrial or milita~ accident. A study was performed to evaluate the effects of a corticosteroid (dexamethasone) on the hearing loss from a series of blast waves that would simulate an AAT. Groups of chinchillas were exposed individually to ten 160-dB peak ...

OBJECTIVES Metoclopramide is a commonly used drug to treat gastroesophageal reflux disease in infants. Given its widespread use and growing concern about toxicity in this population, we conducted a systematic review of metoclopramide for the treatment of gastroesophageal reflux disease in infants. METHODS We performed a systematic search of PubMed and bibliographies of relevant review article...

BACKGROUND This study was conducted to elucidate if nitric oxide is released by the porcine jejunal mucosa upon selective stimulation of AT2 receptors and the possible involvement of iNOS, and to investigate the presence of jejunal AT1 and AT2 receptors. Young landrace pigs were anaesthetized with ketamine and alpha-chloralose. Jejunal luminal NO output was assessed by intraluminal tonometry an...

In this paper, the contamination level of fourteen elements (Al, Ca, Mg, V, Ti, Na, Mn, As, Br, La, Sm, Sc, U, Yb) from different soil samples of the nuclear reactor surrounding areas in Savar, Bangladesh was investigated with instrumental neutron activation analysis (INAA) method. Generally, neutron activation is most reliable tool for determining the concentration of the trace elements and he...

Increased environmental pollution has necessitated the need for eco-friendly clean-up strategies. Filamentous fungal species from gold and gemstone mine site soils were isolated, identified and assessed for their tolerance to varied heavy metal concentrations of cadmium (Cd), copper (Cu), lead (Pb), arsenic (As) and iron (Fe). The identities of the fungal strains were determined based on the in...

Dioscoreophyllum cumminsii (Stapf) Diels leaves are widely used in the treatment of diabetes, obesity, and cardiovascular related complications in Nigeria. This study investigates the anti-inflammatory and antiobesity effect of aqueous extract of Dioscoreophyllum cumminsii leaves in high-fat diet- (HFD-) induced obese rats. HFD-fed rats were given 100, 200, and 400 mgkg-1 body weight of aqueous...

Black ginseng (BG) has been widely used as herbal treatment for improving physiological function. In order to investigate the neuroprotective action of this herbal medicine, we examined the influence of BG on the learning and memory of rats using the Morris water maze, and we studied the effects of BG on the central cholinergic system and neural nitric oxide synthesis in the hippocampus of rats...

to be palatopharyngeal myoclonus/tremor and posited a direct relationship to metoclopramide. The drug was stopped and her symptoms subsided over approximately 8 hours. Palatopharyngeal myoclonus is typically a slow form of tremor at 1 to 4 Hz. It can involve the pharynx, larynx, diaphragm, and extend to involve even eye muscles. The rhythmic movement can occur both during phonation and at rest....

Rice (Oryza sativa) is an important source of human internal exposure to radionuclides and heavy metals because, worldwide, a large fraction the population consume rice as their daily basic diet. In this study, levels correlation natural radioactivity (232Th, 226Ra 40K) (Pb, Ni Cd) in local sold Enugu urban markets, southeastern part Nigeria, were examined. Possible health implications also eva...