this study was conducted to investigate the correlation between lipid-lowering and bone-protective effects of eicosapentaenoic acid on steroid-induced bonechanges in rats. twenty-one male 10-week-old wistar rats were divided into 3 groups (n = 7 each) and treated with 0.9% nacl sc (group 1) or methylprednisolone 7 mg/kg sc once a week (group 2) or methylprednisolone 7 mg/kg sc once a week + eic...

Abstract Background Acute disseminated encephalomyelitis (ADEM) is an extremely rare complication of COVID-19 vaccination with very few reports worldwide. Concomitant peripheral nervous tissue involvement in ADEM uncommon. Case presentation We report the case a 52 year aged lady who developed headache and focal neurological deficits after 10 days vaccination. Her evaluation suggested optic neur...

Abstract Cutaneous arteritis (CA) is a rare limited form of polyarteritis nodosa (PAN), which usually has benign prognosis and requires less aggressive therapy. Here, we present case CA localized to both skin muscle the same area as lesions. We propose with disorders severe subtype literature review disorders, may require treatment intravenous pulse methylprednisolone, immunosuppressive therapy...

Diabetic ketoacidosis (DKA) is characterized by excessive production of organic acids leading to a low blood pH. Rarely, because of other complicating factors blood pH may be in the alkalemic range and the term diabetic ketoalkalosis has been coined to describe this condition. So far, less than 30 such cases have been reported in the literature. We report a 34-year-old woman who received methyl...

Ocular toxoplasmosis frequently presents as necrotizing retinochoroiditis and, less often, peripapillary chorioretinitis and/or papillitis. The progression from papillitis to has been rarely described. We report the case of a 52-year-old patient living in southern Brazil, who developed right eye and was treated with systemic corticosteroids (prednisone 0.6 mg/kg/day pulse therapy methylpredniso...

INTRODUCTION Henoch-Schönlein purpura is an immunoglobulin A-mediated, small vascular inflammatory disease that can be associated with palpable purpura, arthralgia, abdominal pain, or nephritis. The presence of purpura facilitates the diagnosis of Henoch-Schönlein purpura at the onset of associated symptoms, whereas the absence of purpura makes the diagnosis challenging. It is important to diag...

       We are presenting a case illustrating atrial fibrillation (AF) following the use of methylprednisolone in a patient with pelvic and femur fracture. A 48- year- old man with no significant past medical history, was admitted to the emergency department after injury in a car accident. He suffered a multiple bone fracture with chief complaints of pain and shortness of breath. He was transfer...

A 10 yr old male with hypoxaemia, progressive infiltration on the chest radiograph and biopsy-proven desquamative interstitial pneumonia was treated with daily oral prednisolone for 6 months. Intravenous methylprednisolone pulses were concomitantly administered in doses averaging 10 mg x kg body weight(-1) on three consecutive days every 4-6 weeks. After 6 months improvement could be noted and ...