Enzyme selectivity towards a particular enantiomeric configuration of substrate is necessarily governed by chemical and spatial relationships between the substrate and the enzyme binding cavity. In the case of Candida antarctica lipase B experimental evidence shows that enantioselectivity of the enzyme towards the alcohol moiety 3-methyl-2-butanol varies significantly with respect to the chain ...

the glass transition temperature of several pvac(1)-b-poly(ma-co-mma) (2) terpolymers with different fractions of methyl acrylate (ma) and methyl methacrylate (mma) repeating units in random copolymer (block 2) were calculated with barton, kwei and topological equations. the calculation was on the basis of the correlation between the fraction of repeating units in random copolymers and theoreti...

Several methods (e.g., UV/H2O2 oxidation, adsorption, flocculation-precipitation) are normally employed to remove dye from water. A new technique based on liquid/liquid extraction using reverse micelles is proposed whereby recovery of solvent and reuse of dye is possible. Experiments were conducted by mixing a known quantity of dye in aqueous phase and solvent-containing surfactants in a simple...

r\Tumerous investigations are being carried out at present to determine the behavior of the functional groups of protein molecules toward specific reagents. For example, the carboxyl group is suspected of being a possible active site for the binding of some metal ions to proteins. To throw further light upon studies of metal binding, it is of great importance to prepare suitable homogeneous der...

The stainability of neural elements is determined during the various stages of tissue preparation which precede impregnation. The hypothesis (Romanes, 1950) that variations in the physiological state of the neurones at the time of fixation might influence the stain was examined. Feeding and anaesthesia did not influence the staining of gastric nerve fibres under the conditions of the experiment...

Hueper has contributed extensively to knowledge of the effects of the injection into animals of non-metabolizable colloidal substances. In 1939 he reported storage of subcutaneously or intravenously injected polyvinyl alcohol in the reticulo-endothelium of liver, spleen, and lymph nodes, in the endothelium of cerebral, pulmonary, and renal vessels, in the histiocytes of various organs, and in t...

The central amygdala (CeA) has a role for mediating fear and anxiety responses. It is also involved in emotional imbalance caused by alcohol abuse and dependence and in regulating relapse to alcohol abuse. Growing evidences suggest that excitatory glutamatergic and inhibitory γ-aminobutyric acid-ergic (GABAergic) transmissions in the CeA are affected by chronic alcohol exposure. Human post-mort...