The endotelio- and cardioprotective effects of vitamin B6 (2 mg/kg) folic acid (0.2 upon modeling methionine-induced hyperhomocysteinemia via methionine intragastric administration at a dose 3 g/kg were studied. It was shown that the combined use allows on background significant reduction in homocysteine concentrations normalizing endothelial dysfunction coefficient parameters maximum left vent...

Methionine is an amino acid that extremely important for human health. To better understand the biochemical events occurring in body, excess molar properties of methionine and aqueous ethanol methanol mixtures were determined at 298.15 K. Interactions between components solutions are explained. Negative deviations from ideal state have been observed due to hydrogen bonds, dipole interactions, c...

Background—Hyperhomocysteinemia (HHcy) is a reliable indicator of cardiovascular disease, in part because of the production of superoxide and scavenging of nitric oxide (NO). The present study assessed the impact of HHcy on the NO-dependent control of cardiac O2 consumption and examined enzymatic sources of superoxide. Methods and Results—Rats and mice were fed methionine in drinking water for ...

In the sand-fly mid gut, Leishmania promastigotes are exposed to acute changes in nutrients, e.g. amino acids (AAs). These metabolites are the main energy sources for the parasite, crucial for its differentiation and motility. We analysed the migratory behaviour and morphological changes produced by aliphatic, monocarboxylic, dicarboxylic, heterocyclic and sulphur-containing AAs in Leishmania a...

Introduction: Feathers are important body structures that act as surface insulators to reduce maintenance energy requirements and also to protect skin against abrasions and infection. The purpose of this study is to investigate the effects of methionine injection into the yolk sac on development of feather follicle in chicken embryo. Methods: 50 fertilized eggs (weighting 50±0.4 gr) of Ross×...