background consumption of home-distilled alcohol may lead to epidemic or sporadic cases of severe acute methanol poisoning. the difficulty of establishing strict indications for hemodialysis in acute methanol poisoning is a widely recognized issue. materials and methods the determination of the clinical, especially hemodialysis, and para clinical factors influencing patient survival in 46 acute...

Electron solvation in methanol anion clusters, (MeOH)(n) (-) (n approximately 70-460), is studied by photoelectron imaging. Two isomers are observed: methanol I, with vertical binding energies (VBE) ranging from 2-2.5 eV, and methanol II, with much lower VBE's between 0.2 and 0.5 eV. The VBE's of the two isomers depend linearly on n(-1/3) with nearly identical slopes. We propose that the excess...

Methanotrophs in enrichment cultures grew and sustained atmospheric methane oxidation when supplied with methanol. If they were not supplied with methanol or formate, their atmospheric methane oxidation came to a halt, but it was restored within hours in response to methanol or formate. Indigenous forest soil methanotrophs were also dependent on a supply of methanol upon reduced methane access ...

Effects of methanol on colony-formation of human hepatoma cells were investigated. Among five human hepatoma cell lines (Hep G2, HLE, HuH-6, HuH-7, and PLC/PRF/5), only HLE cells showed enhanced colony formation due to methanol. The effective concentrations of methanol were around 1%. The enhancement occurred in a greater degree when the cells were seeded in the culture medium containing methan...

J ^ ^^ r r I c Accepted for publication July 39, 1971 C3 A C MAJCKIDwIQ, Edwina Arm JAcx H. Mai+mzzsoN : Blood methanol corcentrntlone during experimentally induced ethanol intoxication in alcoholics. J. Pbarmacol. Exp. Ther. 179: 29;300, 1971. Accumulation of methanol in blood was detected in alcoholic subjects during a 10to 15-day period of chronic alcohol intake. Blood methanol levels increa...

Mouse embryos develop exencephaly when dams are exposed by inhalation to high concentrations (> or = 10,000 ppm) of methanol on gestational day 8 (GD8; copulation plug = GD0). The present study examined the role of formate, an oxidative metabolite of methanol, in the development of methanol-induced exencephaly in CD-1 mice and cultured mouse embryos. The pharmacokinetics and developmental toxic...

Methanol has been historically considered an exogenous product that leads only to pathological changes in the human body when consumed. However, in normal, healthy individuals, methanol and its short-lived oxidized product, formaldehyde, are naturally occurring compounds whose functions and origins have received limited attention. There are several sources of human physiological methanol. Fruit...

Gasoline engine exhaust has been considered as a major source of air pollution in China. Due to lower cyto- and geno-toxicity effects of methanol engine exhaust, methanol is regarded as a potential substitute for gasoline. We have previously compared cyto- and geno-toxicities of gasoline engine exhaust with that of methanol engine exhaust in A549 cells (Zhang et al., 2007).To characterize the i...

Reanmongkol, W., Subhadhirasakul, S. and Bouking, P. Antinociceptive and antipyretic activities of extracts and fractions from Dracaena loureiri in experimental animals Songklanakarin J. Sci. Technol., 2003, 25(4) : 467-476 Dried coarsely powdered material from the stem woods of Dracaena loureiri Gagnep (D loureiri) has extracted with hexane and methanol to give hexane and methanol extracts, re...

BACKGROUND Pichia pastoris is an established eukaryotic host for the production of recombinant proteins. Most often, protein production is under the control of the strong methanol-inducible aox1 promoter. However, detailed information about the physiological alterations in P. pastoris accompanying the shift from growth on glycerol to methanol-induced protein production under industrial relevant...