نتایج جستجو برای: metastases
تعداد نتایج: 54820 فیلتر نتایج به سال:
In the pre-tyrosine kinase inhibitors (TKIs) era, non-small cell lung cancer (NSCLC) patients with de novo bone metastases had a worse prognosis than those without. However, whether epidermal growth factor receptor (EGFR)-TKIs affect the outcomes of EGFR mutant NSCLC patients with de novo bone metastases has not been well studied thus far. We retrospectively studied the effect of EGFR mutation ...
We assessed the use and outcomes of first- second-line chemotherapy in patients diagnosed with metastatic triple-negative breast cancer (mTNBC). All consecutively mTNBC 2014-2020 ten Dutch hospitals were retrieved from SONABRE registry (NCT-03577197). Last follow-up was collected 2022. The proportion starting a specific line therapy using competing risk method. Median progression-free survival ...
Objective: Colon/rectum cancer often presents with intrapulmonary metastases. Surgical resection can be performed in a selected group of patients. In this study, the search for possible prognostic factors of patients with primary colon/rectum cancer and lung metastases was performed. Methods: Medical records of 110 patients operated on pulmonary metastases of primary colon/rectum cancer were re...
60-year-old woman was treated for a brain metastasis. The patient received intensity-modulated radiation therapy (SIB-IMRT) dose of 30 Gy for the whole brain and 40 Gy delivered simultaneously to individual brain metastases in 10 fractions. The present report investigated the influence of applied novel prepared treatment plan, among others the fractionation protocol on the electroencephalogram ...
Pancreatic metastases are rare. Melanoma, lung cancer and breast carcinoma are the most common origin of pancreatic metastases, whereas renal cell carcinoma is counted in only 1-2%. Renal cell carcinoma usually leads to a solitary pancreatic metastasis, whereas multiple pancreatic metastases are uncommon. We present three cases of multiple hypervascular pancreatic metastases from renal cell car...
Adenocarcinoma no otherwise specified (NOS) and polymorphous low-grade adenocarcinoma (PLGA), are malignant tumors of the salivary glands. Both types have potential for recurrence distant metastases. Rare cases metastases lead to absence standardized systemic therapy gland cancer. This case report aims expand literature regarding parotid adenocarcinoma. We a 54-year-old woman who complained rec...
Brain metastases are a frequent complication in patients with lung cancer and a significant cause of morbidity and mortality. The prognosis of these patients is poor. Medical therapies for brain metastases are neither well-studied nor established. This review analyzes the impact of medical treatment on survival by reviewing recent articles of the management of brain metastases from lung cancer ...
The vast majority of patients with metastatic castration-resistant prostate cancer (mCRPC) develop bone metastases. Bone metastases are a source of significant morbidity and affect quality of life in these patients. Several bone-targeting agents are approved for the treatment of bone metastases in prostate cancer, including bisphosphonates, denosumab, and radiopharmaceuticals. Radium-223 is a n...
BACKGROUND Addition of whole-brain irradiation (WBI) to radiosurgery for treatment of few cerebral metastases is controversial. This study aimed to create an instrument that estimates the probability of developing new cerebral metastases after radiosurgery to facilitate the decision regarding additional WBI. METHODS Nine characteristics were investigated for associations with the development ...
BACKGROUND The development of endocrine tumours of the duodenopancreatic area (ETDP) is thought to be slow, but their natural history is not well known. The aim of this study was to determine the factors that influence survival of patients with ETDP. PATIENTS/METHODS Eighty two patients with ETDP (44 non-functioning tumours, 23 gastrinomas, seven calcitonin-secreting tumours, four glucagonoma...
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