نتایج جستجو برای: metallothioneins

تعداد نتایج: 771  

Journal: :Nucleic acids research 1994
E Brugnera O Georgiev F Radtke R Heuchel E Baker G R Sutherland W Schaffner

Metallothioneins (MTs) are small cysteine-rich proteins that bind heavy metal ions such as zinc, cadmium and copper with high affinity, and have been functionally implicated in heavy metal detoxification and radical scavenging. Transcription of metallothioneins genes is induced by exposure of cells to heavy metals. This induction is mediated by metal-responsive promoter elements (MREs). We have...

Journal: :Molecular and cellular biology 2003
Bo Zhang Oleg Georgiev Michael Hagmann Cagatay Günes Mirjam Cramer Peter Faller Milan Vasák Walter Schaffner

Metallothioneins are small, cysteine-rich proteins that avidly bind heavy metals such as zinc, copper, and cadmium to reduce their concentration to a physiological or nontoxic level. Metallothionein gene transcription is induced by several stimuli, notably heavy metal load and oxidative stress. Transcriptional induction of metallothionein genes is mediated by the metal-responsive transcription ...

2016
Maria V. Brundo Roberta Pecoraro Fabio Marino Antonio Salvaggio Daniele Tibullo Salvatore Saccone Vincenzo Bramanti Maria A. Buccheri Giuliana Impellizzeri Viviana Scuderi Massimo Zimbone Vittorio Privitera

The effect of the nanoparticles on the marine organisms, depends on their size, chemical composition, surface structure, solubility and shape. In order to take advantage from their activity, preserving the surrounding environment from a possible pollution, we are trying to trap the nanoparticles into new nanomaterials. The nanomaterials tested were synthesized proposing a ground-breaking approa...

Journal: :Environmental Health Perspectives 1986
M Beltramini K Lerch

When Neurospora crassa is grown in the presence of Cu(II) ions, it accumulates the metal with the concomitant synthesis of a low molecular weight copper-binding protein. The molecule binds 6 g-atom of copper per mole protein (Mr = 2200) and shows a striking sequence homology to the zinc- and cadmium-binding vertebrate metallothioneins. Absorption, circular dichroism, and electron paramagnetic r...

Journal: :The Journal of nutrition 1979
S H Oh H Nakaue J T Deagen P D Whanger G H Arscott

Two experiments were conducted with Hubbard broiler chicks on the metabolism of high levels of dietary zinc. In the first experiment, chicks were fed a basal diet or the basal diet plus 500, 1,000, 2,000 or 4,000 ppm zinc, and in the second experiment chicks were fed the basal diet or the basal diet plus 1,000, 2,000, 4,000, 8,000 or 16,000 ppm zinc, using zinc acetate. Zinc was found to be ass...

2017
Artur Krężel Wolfgang Maret

Recent discoveries in zinc biology provide a new platform for discussing the primary physiological functions of mammalian metallothioneins (MTs) and their exquisite zinc-dependent regulation. It is now understood that the control of cellular zinc homeostasis includes buffering of Zn2+ ions at picomolar concentrations, extensive subcellular re-distribution of Zn2+, the loading of exocytotic vesi...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید