نتایج جستجو برای: metabolic detoxification
تعداد نتایج: 224739 فیلتر نتایج به سال:
detoxification of children who are born from substance dependent mothers or those who are substance dependent themselves as a result of being abused by their families is a major concern. this report describes withdrawal symptoms and the way of abstinence in a 2.5 year-old girl who was dependent to opium. âfter that she was given opium for nearly two years suppress withdrawal symptoms, methadone...
Abstract Efficient synthetic techniques for the diversification of natural products are incremental drug discovery processes pharmaceutical industry because these complex bioactive compounds often require an adjustment properties. Human liver P450 3A4, key player body's detoxification system and decisive factor a drug's metabolic fate, is renowned its broad substrate scope including many produc...
Recent genome-wide association studies (GWAS) with metabolomics data linked genetic variation in the human genome to differences in individual metabolite levels. A strong relevance of this metabolic individuality for biomedical and pharmaceutical research has been reported. However, a considerable amount of the molecules currently quantified by modern metabolomics techniques are chemically unid...
Metabolism is an organism's primary defense against xenobiotics, yet it also increases the production of toxic metabolites. It is generally recognized that phenolic xenobiotics, a group of ubiquitous endocrine disruptors, undergo rapid phase II metabolism to generate more water-soluble glucuronide and sulfate conjugates as a detoxification pathway. However, the toxicological effects of the comp...
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