Plant mitochondrial NAD-malic enzyme (NAD-ME), which is composed of α- and β-subunits in many species, participates in many plant biosynthetic pathways and in plant respiratory metabolism. However, little is known about the properties of woody plant NAD-MEs. In this study, we analyzed four NAD-ME genes (PtNAD-ME1 through PtNAD-ME4) in the genome of Populus trichocarpa. PtNAD-ME1 and -2 encode p...

Background: The purpose of this study was to examine the occurrence of accidental microembolic signals (MES) and its clinical relevance in patients receiving routine transcranial Doppler (TCD) examinations. Methods: We retrospectively reviewed our institutional TCD database (from January 2007–November 2012). The arteries with positive MES, the presumed sources of emboli and the clinical backgro...

Background: Recently, there has been much more interest in the use of medicinal plants in search of novel therapies for human neurodegenerative diseases such as epilepsy. In the present study, we investigated the anticonvulsant effects of Viola tricolor (V. tricolor) on seizure models induced by pentylenetetrazol (PTZ) and maximal electroshock stimulation (MES). Methods: Totally, 260 mice were ...

Background and Objectives: There is convincing evidence that subjects concomitantly affected by type 2 diabetes (T2D) and metabolic syndrome (MeS) are at greater risk for cardiovascular disease (CVD). Many metabolic derangements in T2D might be attributed to poor vitamin D status. The purpose of this study was to investigate the associations among vitamin D status, MeS and glycemic status in su...

New Interactive, attractive and device independent web application’s Graphical User Interfaces (GUI) are developed by new technologies like Silverlight and Moonlight. Silverlight is Microsoft's cross platform runtime and development technology for running Web based multimedia applications in windows platform. Moonlight is an open-source implementation of the Silverlight development platform for...

the aim of the study was to determine the prevalence of metabolic syndrome (mes) in professional bus drivers, and its association with overtime working hours among those drivers in urmia, iran. in this cross sectional study the studies population was 626 professional bus drivers, aged 20-69 yr. the mes (according to thenational cholesterol educationprogram adult treatment panel iii), waist circ...

During Caenorhabditis elegans embryogenesis the primordial germ cell, P(4), is generated via a series of unequal divisions. These divisions produce germline blastomeres (P(1), P(2), P(3), P(4)) that differ from their somatic sisters in their size, fate and cytoplasmic content (e.g. germ granules). mes-1 mutant embryos display the striking phenotype of transformation of P(4) into a muscle precur...

With a binary response Y, the dose-response model under consideration is logistic in flavor with pr(Y=1 | D) = R (1+R)(-1), R = λ(0) + EAR D, where λ(0) is the baseline incidence rate and EAR is the excess absolute risk per gray. The calculated thyroid dose of a person i is expressed as Dimes=fiQi(mes)/Mi(mes). Here, Qi(mes) is the measured content of radioiodine in the thyroid gland of person ...

Medication Errors (MEs) as one of the most important medical errors in hospitals are common, expensive, and sometimes harmful to patients. Several strategies such as Computerized Provider Order Entry (CPOE) and wristband barcoding are used for decreasing MEs. The role of new technologies is emphasized in the policies and planning in the health system in Iran. Worldwide, CPOE is a new technology...

PURPOSE. A new series of substituted quinoline-2(1H)-one and 1,2,4triazolo[4,3-a]-quinoline derivatives were designed and synthesized to meet the structural requirements essential for anticonvulsant properties. METHODS. 4-substituted-phenyl3,4-dihydro-2(1H)-quinolines, 5-substitutedphenyl-4,5-dihydro-1,2,4-triazolo[4,3a]quinolines and 5-substituted-phenyl-4,5-dihydro-1,2,4triazolo-[4,3-a]quinol...