There is evidence from well designed randomised controlled trials that modern medical and conservative surgical therapies (including endometrial ablation) are effective treatments for heavy menstrual bleeding for many women. Submucous fibroids may be resected directly via the hysteroscope, reducing menstrual bleeding, although data are available only from case series. Endometriosis is common, m...

in order to assess the efficacy of hysteroscopic endometrial ablation and factors which are important in it's success, a prospective, randomized study was performed in shiraz university hospitals between sep. 1995 to feb. 1998. 50 patients with chief complaints of menorrhagia that were in reproductive age (25- 50 years) and had shown no response to medication and d&c; underwent endometrial...

We report a rare case of acquired vitamin K deficiency presenting with severe menorrhagia and without any gynecological problem. Partial thromboplastin time (59.2 seconds) and prothrombin time (33.1 seconds, INR: 5.97) were considerably prolonged in laboratory evaluations. A complete coagulation factor assay test was performed for the patient: factor IX, 24%; factor II, 41%; factor VII, 3%; and...

Uterine fluid was collected from a group of normal patients and a group of patients with menorrhagia. Heparin-like activity was detected in 34 out of 38 samples using an anti-Xa heparin assay. The heparin-like activity in uterine fluid was inhibited by adding the heparin antagonist hexadimethrine bromide to the assay. Concentrations of fibrinogen-fibrin degradation products (FDPs) were measured...

Background: Hypothyroidism is associated with a wide spectrum of reproductive disorders ranging from abnormal sexual development, menstrual irregularities, and infertility. The present study was conducted to assess thyroid in age group.Materials Methods: 84 women group 15-45 years were divided patients into 2 groups 42 each. Group I II other than disorders. Parameters such as parity, menarche, ...

Thorne for data entry; and Janet Darbyshire, Vikki Entwistle, David Girling, Joan Houghton, Richard Lilford, Sandy Oliver, John Stewart, Hazel Thornton, and Sarah Walker for their helpful comments. Contributors: The survey was suggested by IC. All authors contributed to designing the questionnaire. BH and AT conducted the survey. AK designed and developed the database. DE, BH, AK, and AT analys...

Background: To compare the clinical efficacy tranxamic acid and Ibuprofen in the treatment of ovulatory menorrhagia. Materials and Methods: This randomized controlled trial was performed at my office one hundred women with ovulatory hemorrhagic were randomized to take one of two treatment regimens during four consecutive cycles: tranexamic acid 3gr daily on day 1-5, ibuprofen 1200 mg daily. Res...

Menorrhagia is a common problem in women and increasing numbers are seeking help and advice regarding management. In many cases, surgery is not appropriate and so awareness of alternative treatments is important. The aim of this review is to summarise the evidence available regarding current medical therapies.