There is a strong advocacy movement for large doses of vitamin C. Some authors argue that the biological half-life for vitamin C at high plasma levels is about 30 minutes, but these reports are the subject of some controversy. NIH researchers established the current RDA based upon tests conducted 12 hours (24 half lives) after consumption. The dynamic flow model refutes the current low-dose rec...

Un organite d'ultrastructure typiquement mitochondriale a t6 rcemment observe chez les trypanosomes, en troite association avec le kin6tonucleus (3, 6-8, 17). Cette meme association a 6t6 trouvee chez un bodonide (14). Bien que de forme assez variable, cet organite est generalement allong6 et a souvent 6t6 decrit sous l'aspect d'un long tube ou canal (6, 7) sinueux, allant du kin6tonucleus chac...

Meta-programming is a well-known technique widely used in logic programming and artificial intelligence. Meta-interpreters are powerful tools especially for writing expert systems in general and for writing their inference machines in particular. While the classical approach to meta-interpretation is based on the syntactic definition of a meta-interpreter, new approach presented in this paper c...

With the advent of the Model Driven Architecture, models are replacing code as the major artifact in software development. A critical success factor for this is the possibility to derive models from each other in terms of transformations. Existing approaches, such as the forthcoming QVT-standard, will provide a proper foundation for transforming models on a fine-grained level. They, however, do...

MELAS syndrome (mitochondrial cytopathy, encephalomyopathy, lactic acidosis and stroke like episodes) is a syndrome in which signs and symptoms of gastro-intestinal disease are uncommon, if not rare. We describe a young female patient who presented as an acute surgical emergency, diagnosed as toxic mega colon necessitating an emergency total colectomy; the diagnosis of MELAS syndrome was made p...

The rate of forest destruction has accelerated sharply in Brazilian Amazonia, but there are also vital conservation opportunities with the ongoing designation of important new protected areas. In a timely paper, Carlos Peres argues that an extensive network of mega-reserves, operationally defined as those exceeding 1 million ha in area, is needed to ensure the long-term persistence of Amazonian...

was small, and that they usually occurred within 20 weeks. Leifer (1945), using a total dosage of 1-2 mega units of penicillin given in sixty 3-hourly injections, noted that eight patients relapsed out of a total of 96; and that six of these relapses occurred during the 4th month, one at 6 months, and one at 13 months after treatment. Downing (1950) has recently drawn attention to one case of e...

BACKGROUND Atrial fibrillation (AF) is the most common cardiac arrhythmia, and it increases in prevalence with advancing age to about 5% in people older than 65 years. CASE PRESENTATION We present a rare case of atrial fibrillation secondary to a mega-oesophagus occurring in an 84-year-old Caucasian woman. The patient had a history of progressive dysphagia and the accumulation of food debris ...

seen as designed mega-analyses, and the necessary databasing, data-sharing and analysis tools are emerging (Keator et al., 2008, 2009; Bockholt et al., 2009). In the following, current limitations in function-location brain mapping are examined, along with strategies for their remediation through data pooling. Following the meta/mega-analysis distinction frequently employed in the fi eld, the a...

Background: Health benefits of vitamin D has been proved by a large number of studies, however, to the best of our knowledge there has been no study investigating the effect of mega dose of vitamin D on gestational diabetes mellitus (GDM). This study was the first to assess the effect of postpartum injection of mega dose of vitamin D on blood pressure (BP) in GDM. Methods: This is a randomized ...