The present work investigated the potential of compensator-based intensity-modulated radiation therapy (CB-IMRT) as an alternative to multileaf collimator (MLC)-based intensity-modulated radiation therapy (IMRT) to treat malignant pleural mesothelioma (MPM) post extrapleural pneumonectomy. Treatment plans for 4 right-sided and 1 left-sided MPM post-surgery cases were generated using a commercia...

Abstract In this paper we discuss design considerations and beam dynamics challenges associated with laser-driven plasma-based accelerators as applied to multi-TeV-scale linear colliders. Plasma provide ultra-high gradients ultra-short bunches, offering the potential for compact linacs reduced power requirements. We show that stable, efficient acceleration quality preservation is possible in no...

Linear accelerators used in radiation therapy treatments usually provide the capability of irradiating with different dose rates. The medical physicist may choose arbitrary the dose rate to use, although the relative biological effectiveness (RBE) varies with this physical parameter. In this work the measurements of absorbed dose of the x-ray beams from a Varian 6 MV linear accelerator CLINAC 6...