Citation style for this article: Eurosurveillance editorial team. Stepping up European measles surveillance. For many years Eurosurveillance has made it a point to publish articles on measles outbreaks and measles prevention and control in Europe. The purpose has always been to increase awareness about this dangerous and potentially fatal infectious disease and highlight opportunities for preve...

The interplay between autophagy and intracellular pathogens is intricate as autophagy is an essential cellular response to fight against infections, whereas numerous microbes have developed strategies to escape this process or even exploit it to their own benefit. The fine tuned timing and/or selective molecular pathways involved in the induction of autophagy upon infections could be the corner...

macular or maculopapular skin reactions are frequent events in skin allergies as well as in viral infections. clinically, the differentiation may be difficult in the absence of a clear relationship with drug intake or in the failure to detect measles virus-specific antibodies. studies on drug-specific t cell lines and t cell clones isolated from skin-allergy patients have suggested that these c...

On April 15, 2016, local public health officials in Shelby County, Tennessee, were notified of a positive measles immunoglobulin M (IgM) test for a male aged 18 months (patient A). On April 18, 2016, a second positive measles IgM test was reported for a man aged 50 years (patient B). Both patients had rash onset on April 9, 2016. The Shelby County Health Department initiated an investigation, a...

Purified hemagglutinin and fusion glycoproteins of measles virus either in soluble form or inserted in artifical membranes bind to human peripheral blood lymphocytes and induce cell-mediated cytotoxicity (CMC) in a dose-response fashion. Both autologous and heterologous noninfected target cells are lysed in vitro. The expression of CMC is not inhibited by anti-measles virus antibody added to ly...

Idiopathic interstitial pneumonias include complex diseases that have a strong interaction between genetic makeup and environmental factors. However, in many cases, no infectious agent can be demonstrated, and these clinical diseases rapidly progress to death. Theoretically, idiopathic interstitial pneumonias could be caused by the Epstein-Barr virus, cytomegalovirus, adenovirus, hepatitis C vi...

Virus-induced cell fusion has been studied after infection of Vero cells with measles virus. Scanning and transmission electron microscopy were combined with immunoperoxidase labeling of measles antigens to correlate viral production and distribution of virus-induced erythrocyte binding sites with progress of fusion. Release of infectious virus started before syncytia were detected and decrease...

Measles is a highly infectious and contagious disease of the respiratory system caused by Morbilivirus (Hashiguchi et al., 2011). The clinical disease has been characterized by high fever , cough, conjunctivitis, coryza, malaise, maculopapular rash and erythematous patches throughout the body along with increased mortality among non-vaccinated children (Ellison, 1931; Fazlalipour et al., 2008)....

The neurovirulence of two wild type (wt) and seven Subacute Sclerosing Panencephalitis (SSPE) measles virus strains was tested in young adult ferrets by intracerebral (IC) inoculation of infected Vero cell suspensions. Wt strains Edmonston and Woodfolk and SSPE strains Mantooth, Halle, and LEC-S did not produce a detectable encephalitis in the ferrets, but caused a significant formation of seru...

We studied eight children who had measles at 6 to 10 months of age during the 1998 Argentine measles outbreak and in whom subacute sclerosing panencephalitis developed 4 years later. We report the genetic characterization of brain tissue–associated measles virus samples from three patients. Phylogenetic relationships clustered these viruses with the wild-type D6 genotype isolated during the 199...