Various ocular disorders remain a major concern for medical care providers and health policy makers. Only in the US more than 6.6 million people were affected by blindness in 2011 (1). Meanwhile, even though people mostly inhabit low or moderate altitudes, about 140 million people worldwide live above 2500 meters (2). Therefore, association between various vision disorders and high altitude rem...

P-bodies are specialized cytoplasmic compartments where translational repression and mRNA turnover may occur. Findings in this issue of Cell provide evidence that P-bodies are sites of "mRNA purgatory." Bhattacharyya et al. (2006) reveal that normal mRNA can be released from P-bodies and translated into protein in response to stress. Meanwhile, Sheth and Parker (2006) report that aberrant mRNAs...

An adaptive feedback method for tracking and stabilizing unknown or slowly varying saddle type steady states of conservative dynamical systems is described. We demonstrate that a conservative saddle point can be stabilized with neither unstable nor stable filter technique. Meanwhile, a controller, involving both filters in parallel, works perfectly. As a specific example, the Lagrange point L2 ...

Based on the characteristics of perishable goods, we extend the location-routing problem with distance constraints by adopting chance constrained goal programming approach to solve the uncertainty and to express the different priority levels of decisions. The random of depot construction costs and vehicle routing travel time is taken into account. Meanwhile, a two-stage genetic algorithm incorp...

The mobile phone has transitioned from its traditional role as a mere communications medium to that of an essential multipurpose personal gadget. Consider that the number of smartphone users worldwide will surpass two billion in 2016, according to new forecasts from eMarketer. Meanwhile, technological advancements and the proliferation of devices across platforms and operating systems (Apple iO...

In this paper, Haar wavelet operational matrix method is proposed to solve a class of fractional partial differential equations. We derive the Haar wavelet operational matrix of fractional order integration. Meanwhile, the Haar wavelet operational matrix of fractional order differentiation is obtained. The operational matrix of fractional order differentiation is utilized to reduce the initial ...

While studying the first principle of thermodynamics under relativistic conditions, nobody in the 20th century took into consideration a surface tension; meanwhile this thermodynamic parameter is as important as the pressure p. Both Planck with his disciple and Einstein wrote down the first principle of thermodynamics under relativistic conditions neglecting the surface tension as well. Besides...

Methods The “Comite de Protection des Personnes Sud-Est Mediterranee V” did not consider this research as interventional. Implementation of the guidelines concerning four areas: (i) unit organization; (ii) patient management; (iii) support for families; (iv) support for caregivers have been studied in the RIRE intensive care network. Meanwhile, we collected anonymously the caregivers’ burnout s...

Based on the characteristics of the attitude control system, this paper use the neural network predictive model controller which can identify accurately attitude system and obtain real-time control sequence applied to the controlled object through the model prediction, feedback correction and rolling optimization each link to complete motion attitude control of unmanned aerial vehicle. This con...

The direct hydroamination of alkynes driven by visible light can be achieved in high yield and selectivity at ambient temperature using supported gold nanoparticles (AuNPs) as photocatalysts. Aniline molecules interact with visible light activated AuNPs meanwhile alkynes could be activated at active sites on the support. The findings reveal a new green approach for synthesis of fine organic com...