Objective: Associated with insulin resistance in type 2 diabetes are increased serum triglycerides, decreased HDL-C, and a predominance of large VLDL, small LDL, and small HDL particles. The comparative effects of thiazolidinedione insulin sensitizers on serum lipoprotein particle concentrations and sizes in type 2 diabetes are not known. We studied the effects of pioglitazone (PIO) and rosigli...

The influence of polymeric dispersants containing different functional groups on TiO2 pigment particle suspension was investigated at pH 6.0 and 9.5, using rheology and particle size data. The dispersants chosen were polyacrylic acid and modified polyacrylamides including homo and copolymers modified with carboxylate and/or hydroxyl groups. The pigment suspension was strongly affected by both p...

BACKGROUND Subjects with type 2 diabetes have smaller LDL and HDL particles in addition to higher levels of triglycerides and lower HDL cholesterol. Elevated insulin resistance, blood pressure, and dyslipidemia (including small dense LDL) predicted incident diabetes. In the Insulin Resistance Atherosclerosis Study (IRAS) we studied nuclear magnetic resonance (NMR) lipoprotein particle measures ...

the effect of addition of qodumeh shahri (lepidium perfoliatum) seed gum on the emulsion properties were investigated in this study. l. perfoliatum seed gum with 0-0.6% (w/w) concentration was used together with 2% (w/w) wpc to emulsify 20% (w/w) corn oil. the emulsion was analyzed for emulsion stability, particle size, specific surface area, particle size distribution and rheological propertie...

Dissolution pressure and nozzle temperature effects on particle size and distribution were investigated for RESS (Rapid Expansion of Supercritical Solution) process. Supercritical CO2 was used as solvent and Ibuprofen was applied as the model component in all runs. The resulting Ibuprofen nano-particles (about 50 nm in optimized runs) were analyzed by SEM and laser diffraction pa...

OBJECTIVE To examine sex-specific black/white differences in lipoprotein profile and the role of visceral adiposity and to assess the relationship between insulin sensitivity and lipoprotein profiles in each group. RESEARCH DESIGN AND METHODS Fasting lipoprotein particle size and concentration and visceral adipose tissue (VAT) were determined in 226 children (117 black, 101 male) aged 8 to <1...

AIMS The aim of the study was to examine whether differences in average diameter of low-density lipoprotein (LDL) particles were associated with total and cardiovascular mortality. METHODS AND RESULTS We studied 1643 subjects referred to coronary angiography, who did not receive lipid-lowering drugs. During a median follow-up of 9.9 years, 398 patients died, of these 246 from cardiovascular c...

BACKGROUND We assessed racial differences in lipoprotein particle size, a marker of atherosclerosis risk, among women with coronary disease. METHODS We studied 378 women (33% non-White, predominantly African American) at the baseline visit of the Women's Angiographic Vitamin and Estrogen Trial (WAVE), a multicenter trial of hormone replacement and antioxidant vitamin therapy in postmenopausal...