INTRODUCTION Clinical synovitis is often associated with damage to bone and cartilage. Previous data have suggested that joint erosions (JE) are more prevalent than joint space narrowing (JSN) and that the two processes are partly independent of each other. The objective of this study was to evaluate whether the presence of JE in an individual joint can lead to development of JSN and if existin...

We read with interest the pictorial essay on ultrasonography of bone erosions by Grassi and colleagues. The presented site-specific comparison of radiographic and sonographic imaging of metacarpophalangeal (MCP) and metatarsophalangeal (MTP) joint sites in rheumatoid subjects suggests strongly a homology of the erosive lesions, as visualised by these diVerent imaging modalities. A recently publ...

The present study proposed a method for establishing linkage representation of the human hand skeletal system. Hand skeletons 15 male subjects were reconstructed from computed tomography (CT) scans in 10 different postures selected natural hand-closing motion. wrist joint center was estimated as intersection centerline metacarpal middle finger and distal crease. remaining centers kinematically ...

INTRODUCTION The aim of this study was to assess a novel approach for the quantification of finger joint space narrowing and joint destruction in patients with rheumatoid arthritis (RA) focusing on the peripheral hand articulations. METHODS A total of 280 patients with verified RA underwent computerized semi-automated measurements of joint space distance at the finger articulations based on r...

We read with interest the pictorial essay on ultrasonography of bone erosions by Grassi and colleagues. The presented site-specific comparison of radiographic and sonographic imaging of metacarpophalangeal (MCP) and metatarsophalangeal (MTP) joint sites in rheumatoid subjects suggests strongly a homology of the erosive lesions, as visualised by these diVerent imaging modalities. A recently publ...

INTRODUCTION Residual subclinical synovitis can still be present in joints of rheumatoid arthritis (RA) patients despite clinical remission and has been linked to ongoing radiological damage. The aim of the present study was to assess subclinical synovitis by positron emission tomography (PET; macrophage tracer (11)C-(R)-PK11195) in early RA patients with minimal disease activity without clinic...