نتایج جستجو برای: mcm 41tmspdeta

تعداد نتایج: 3500  

Journal: :Journal of hazardous materials 2011
Liang-Yi Lin Jien-Ting Kuo Hsunling Bai

This study explored the possibility of recovering waste powder from photonic industry into two useful resources, sodium fluoride (NaF) and the silica precursor solution. An alkali fusion process was utilized to effectively separate silicate supernatant and the sediment. The obtained sediment contains purified NaF (>90%), which provides further reuse possibility since NaF is widely applied in ch...

2014
Clifford A Froelich Sukhyun Kang Leslie B Epling Stephen P Bell Eric J Enemark

The ring-shaped MCM helicase is essential to all phases of DNA replication. The complex loads at replication origins as an inactive double-hexamer encircling duplex DNA. Helicase activation converts this species to two active single hexamers that encircle single-stranded DNA (ssDNA). The molecular details of MCM DNA interactions during these events are unknown. We determined the crystal structu...

2017
Hongbin Zhong Bin Chen Henrique Neves Jinchun Xing Youxin Ye Ying Lin Guohong Zhuang Shu-Dong Zhang Jiyi Huang Hang Fai Kwok

Minichromosome maintenance (MCM) proteins play an essential role in DNA replication. They have been shown to be overexpressed in various types of cancer. However, the role of this family in renal cell carcinoma (RCC) is widely unknown. In this study, we have identified a number of RCC datasets in the Gene Expression Omnibus database and also investigated the correlation between the expression l...

2016
Hui Wang Songjin Zhang Xiumei Tian Chufeng Liu Lei Zhang Wenyong Hu Yuanzhi Shao Li Li

Nanoprobes for combined optical and magnetic resonance imaging have tremendous potential in early cancer diagnosis. Gold nanoparticles (AuNPs) co-doped with Gd2O3 mesoporous silica nanocomposite (Au/Gd@MCM-41) can produce pronounced contrast enhancement for T1 weighted image in magnetic resonance imaging (MRI). Here, we show the remarkably high sensitivity of Au/Gd@MCM-41 to the human poorly di...

2011
Kai Chen Yi Zhou Qi Zheng Xiaokang Yang Li Song

Local feature matching is not robust to extract correct correspondences under many conditions, such as images with general deformations and repetitive patterns. To solve this problem, this paper proposes a new geometric constraint method: Maximal Clique Matching (MCM). In MCM, the global geometric constraint problem can be expressed as the maximal clique problem in graph theory. MCM starts from...

Journal: :Molecular and cellular biology 2003
Kevin J Harvey John Newport

In a Xenopus egg replication system, the origin recognition complex (ORC) does not bind to CpG methylated DNA and DNA replication is inhibited. Insertion of low density CpG DNA of at least 1.2 kb into methylated plasmids rescues both replication and ORC binding. Using this pseudo-origin, we find that ORC binding is restricted to low-CpG-density DNA; however, MCM is loaded onto both weakly and h...

2015
Emma L. Hesketh Richard P. Parker-Manuel Yuriy Chaban Rabab Satti Dawn Coverley Elena V. Orlova James P. J. Chong

ATP-dependent DNA unwinding activity has been demonstrated for recombinant archaeal homohexameric minichromosome maintenance (MCM) complexes and their yeast heterohexameric counterparts, but in higher eukaryotes such as Drosophila, MCM-associated DNA helicase activity has been observed only in the context of a co-purified Cdc45-MCM-GINS complex. Here, we describe the production of the recombina...

Journal: :EURASIP J. Adv. Sig. Proc. 2010
Haijian Zhang Didier Le Ruyet Michel Terré

Spectral correlation theory for cyclostationary time-series signals has been studied for decades. Explicit formulas of spectral correlation function for various types of analog-modulated and digital-modulated signals are already derived. In this paper, we investigate and exploit the cyclostationarity characteristics for two kinds of multicarrier modulated (MCM) signals: conventional OFDM and fi...

Journal: :Cell reports 2015
Yun Quan Yisui Xia Lu Liu Jiamin Cui Zhen Li Qinhong Cao Xiaojiang S Chen Judith L Campbell Huiqiang Lou

Mcm2-7 helicase is loaded onto double-stranded origin DNA as an inactive double hexamer (DH) in G1 phase. The mechanisms of Mcm2-7 remodeling that trigger helicase activation in S phase remain unknown. Here, we develop an approach to detect and purify the endogenous DHs directly. Through cellular fractionation, we provide in vivo evidence that DHs are assembled on chromatin in G1 phase and sepa...

2016
Kelly M. Schermerhorn Nathan Tanner Zvi Kelman Andrew F. Gardner

The minichromosome maintenance (MCM) complex is the replicative helicase responsible for unwinding DNA during archaeal and eukaryal genome replication. To mimic long helicase events in the cell, a high-temperature single-molecule assay was designed to quantitatively measure long-range DNA unwinding of individual DNA helicases from the archaeons Methanothermobacter thermautotrophicus (Mth) and T...

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