OBJECTIVES We previously reported favourable short-term results of our 'trans-septal maze procedure', a novel technique for creating biatrial lesions through a septal-superior approach during mitral valve surgery. Here, we reviewed the mid-term results of this procedure and determined the impact of restored left atrial (LA) contraction on late outcomes. METHODS We examined clinical data of 50...

Introduction: The ablation technique is one of the important therapeutic interventions for treatment of AV Nodal tachyarrhythmia. Different animal models have been developed to study the effects of ablation on the functional interanodal structure. The aim of the present study was to develop a new model of computer analysis to produce lesions by using direct voltage in isolated perfused rabbi...

Background: Local ablative treatments play an important role for patients who cannot be treated surgically. Radiofrequency ablation is a well-established alternative to surgical treatment of thyroid nodules, however it also has disadvantages. Microwave ablation (MWA) is a new minimally invasive treatment promising several improvements. The aim of this retrospective study was to evaluate the eff...

Treatment of atrial fibrillation (AF) has evolved significantly during the last 3 decades. Successful surgical AF ablation was developed by the pioneering work of Dr James Cox in 1987 resulting in the development of the Coxmaze (CM) procedure.1 Further experience and incorporation of ablation technology allowed subsequent modifications to increase efficacy and decrease morbidity, resulting in t...

OBJECTIVE Prospective randomised study comparing patients with atrial fibrillation (AF) of more than 6 months duration after mitral valve surgery plus biatrial modified radiofrequency Maze procedure using Medtronic Cardioblate System (Cardioblate group, n=24) vs mitral valve surgery plus intensive rhythm control strategy (control group, n=25). METHODS Patients were blinded to randomisation. P...

Social cooperation is a state in which people work together on shared activity from they both benefit, and the success of each person dependent everyone doing their part. Imagine, for example, basketball game all team members make effort cooperate to win game. To study this kind social lab, we used rats. We created special maze two rats must coordinate behavior as pair, moving through sections ...

Two-pore domain K(+) (K(2P)) channels are thought to underlie background K(+) conductance in many cell types. The Trek subfamily of K(2P) channels consists of three members, Trek1/Kcnk2, Trek2/Kcnk10, and Traak/Kcnk4, all three of which are expressed in the rodent CNS. Constitutive ablation of the Trek1 gene in mice correlates with enhanced sensitivity to ischemia and epilepsy, decreased sensit...

Ligament of Marshall alcohol ablation is a treatment for refractory atrial fibrillation and left flutter. Left appendage (LAA) isolation resulting from LOM has not been described. To describe case which resulted in dissociation reentrant flutter the atria. A middle aged man with history multiple flutters was referred repeat after prior unsuccessful ablations. He previously underwent surgical MA...