A bioassay of thio-TEPA for possible carcinogenicity was conducted by administering the test chemical by intraperitoneal injection to Sprague-Dawley rats and B6C3F1 mice. Groups of 31-39 rats of each sex were administered thio-TEPA in phosphate-buffered saline at one of three doses, either 0.7, 1.4, or 2.8 mg/kg body weight, three times per week for a maximum of 52 weeks, then observed for addi...

It is well known that a skin dose from high-energy x-ray radiation varies with the angle of beam incidence or the presence of a radiotherapy linear accelerator couch top material. This note investigates changes produced to the skin dose from a Varian carbon fibre grid couch top at differing angles of incidence for 6 MV x-rays as is often the case clinically. Results have shown that the skin dos...

PURPOSE: A wide variation in the use of bolus has been observed in postmastectomy radiotherapy (PMRT), which affects dose delivery to skin and may have an impact on locoregional recurrence. However, even treatment planning systems (TPSs) with advanced algorithms do not provide accurate dosimetry in the buildup region. This study aims to perform in vivo measurements of the chest wall (CW) skin d...

X-rays generated at a kilovoltage of 250 have been used in the treatment of malignant disease for about 30 years. It was found that when high doses were given, damage to the skin and subcutaneous tissues was frequent. After desquamation of the skin had subsided, pigmentation followed and during the succeeding i8 months permanent and unsightly telangiectasis developed. This was often associated ...

The dietary intake of vitamin D is currently below the recommended intake of 10-20μg vitamin D/day. Foods with increased content of vitamin D or new products with enhanced vitamin D are warranted. Light-emitting diodes (LEDs) are a potential new resource in food production lines. In the present study the exposure conditions with ultraviolet (UV) LEDs were systematically investigated in the wave...

Introduction: Many people use hot water springs to treat some diseases, such as rheumatism, arthritis, and skin diseases, but they are unaware of the presence of natural radioactive substances that may be found in hot water springs. An effective way to understand the radiation risk of these elements are measuring the dose rate of radiation. In this study, for the first time, ga...

To investigate whether local activity of capsaicin-sensitive sensory afferents in the skin has a modulatory role in the reflex cutaneous vasodilator response to hyperthermia in humans, experiments were conducted in two parts. First, low-dose topical capsaicin (0.025%) was administered acutely to stimulate local activity of these afferents. Second, we temporarily desensitized these nerves in a s...

Introduction: Accurate evaluation of femoral and tibial torsion is essential for children or adult with legs deformity, becuse incorrect legs morphogenesis can lead to pathological situation. CT scan is commonly used for the measurement of skeletal bone parameters. But, disability in imaging from standing and sitting posture and absorb dose of patients are deficits of this meth...

  Introduction: Using beta emitter radionuclide is a useful therapeutic modality in the treatment of skin cancers in areas which are difficult to cure by other methods. The aim of this research is to evaluate the tissue response to beta rays of 166Ho and determine the feasibility of beta emitting radionuclide for treatment of skin cancers. Methods: In this...