نتایج جستجو برای: maternal antibodies
تعداد نتایج: 262981 فیلتر نتایج به سال:
An association between maternal IgG antibodies reactive against proteins in fetal brain and an outcome of autism in the child has been identified. Using a mouse model of prenatal intraventricular administration of autism-specific maternal IgG, we demonstrated that these antibodies produce behavioral alterations similar to those in children with ASD. We previously demonstrated that these antibod...
The fact that antibodies can be conveyed to a newborn animal by colostrum was first shown by Ehrlich (1892). In his experiments artificial antibodies to abrin and ricin were induced in mice; after exchange of litters of immunized and nonimmunized animals, the litters suckled from immunized mothers had acquired some measure of protection to abrin and ricin. Although the antibodies of colostrum a...
Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a disease that may cause severe bleeding complications with risk of perinatal death or lifelong disability. The main cause of FNAIT is maternal antibodies against human platelet antigen (HPA)-1a. Both fetomaternal bleeding and transplacental trafficking of fetal cells during pregnancy could be the cause of alloimmunization. Persistence o...
BACKGROUND Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a bleeding disorder caused by maternal antibodies against paternal human platelet antigens (HPAs) on fetal platelets. Antibodies against HPA-1a are accountable for the majority of FNAIT cases. We have previously shown that high levels of maternal anti-HPA-1a antibodies are associated with clinically significant reduced birth w...
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