The aim of this study was to investigate whether the rs12255372 (TCF7L2) and D76N (PDX-1) polymorphisms are associated with type 2 diabetes mellitus (T2DM) in Mashhad, northeast Iran. A hundred twenty seven patients with T2DM and 71 non-diabetic controls in Mashhad were genotyped by PCR-RFLP and ARMS-PCR methods. Single nucleotide polymorphisms (SNPs) were confirmed by sequencing in some sample...

BACKGROUND Dental unit waterline system is considered potential source for contamination with Legionella species. The aim of this study was to determine if contamination of a dental unit water line system by Legionella pneumophila serogroup1 in the Mashhad School of Dentistry occurred in 2009. METHODS A total of 52 dental units were selected from all clinical departments of the Mashhad School...

OBJECTIVES The population in Iran is a genetic admixture of the ancestral Aryan and other populations neighboring Iran. Different ethnic groups in Iran show wide regional distributions for many human leukocyte antigen (HLA) alleles. Therefore, it is necessary and sensible to study the differences in HLA allele distribution in different area. We studied the HLA class I and II allele frequencies ...

Determination of Critical Channel Using Combination ASSA and GIS Models in Different Return Periods (Case Study: Mashhad Municipality9 District)

OBJECTIVE This cross-sectional study was carried out to determine the prevalence of overweight and obesity among secondary school children aged 12 to 14 years in the city of Mashhad, Iran and its association with parental body mass index. METHODS A total of 1189 secondary school children (579 males and 610 females) aged 12- 14 years old were selected through a stratified multistage random sam...

BACKGROUND Pilonidal is a painful disease which occurs mainly in the sacrococcygeal area. In 1833 Herbert Mayo first reported a case of a young woman with a hair-containing sinus in the sacrococcygeal area. In 1880, Hodge suggested the term "pilonidal" from the Latin "pilus" for hair and "nidus" meaning nest. OBJECTIVES Effect of using autologous platelet-rich plasma (PRP) on pain reduction i...

every year, a part of the national capital of the country is lost due to the disorders of traffic. an important part of the traffic disorders is caused by the improper behavior of some users of urban transport system. such a situation is contrary to the principles of smart growth and urban sustainability. the study of traffic conflicts as a symbol of the society culture of traffic can lead city...

BACKGROUND Health warning labels on cigarette packages are among the most straightforward and important tools to communicate with smokers and various studies have illustrated their efficacy. OBJECTIVES The current study aimed to investigate the opinions of male smokers in Mashhad city about the efficacy of health warning labels printed on cigarette packages on the smoking status of smokers. ...