hirschsprung's disease, also known as congenital aganglionic megacolon, is a congenital disorder which develops due to an absence of neural ganglia in a segment of large bowel. most commonly, the rectum or rectosigmoid, and rarely other areas or the entire colon are involved. in this disease, all three neural plexi, i.e., the myenteric (auerbach's) plexus, the superficial submucosal (...
